Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins
| Autor Corporativo: | |
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| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2017.
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| Edición: | 1st ed. 2017. |
| Colección: | Milestones in Drug Therapy,
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| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/978-3-319-46877-8 |
Tabla de Contenidos:
- Chemical Assembly of Antibody-Drug Conjugates
- Pre-clinical evaluation of ADCs delivering highly potent pyrrolobenzodiazepine (PBD) dimers
- Stable and homogeneous drug conjugation by sequential bis-alkylation at disulfide bonds using bis-sulfone reagents
- Calicheamicin antibody-drug conjugates for liquid- and solid tumor indications
- Enzyme-based strategies to generate site-specifically conjugated Antibody Drug Conjugates
- Substance P – Saporin for the Treatment of Intractable Pain
- Recombinant immunotoxins for Chronic Inflammatory Disease
- BL22: A milestone in targeting CD22.