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Tubulin-Binding Agents Synthetic, Structural and Mechanistic Insights /

Tubulin-Binding Agents Synthetic, Structural and Mechanistic Insights /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Carlomagno, Teresa. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2009.
Edition:1st ed. 2009.
Series:Topics in Current Chemistry, 286
Subjects:
Medicinal chemistry.
Biochemistry.
Cancer research.
Organic chemistry.
Analytical chemistry.
Medicinal Chemistry.
Biochemistry, general.
Cancer Research.
Organic Chemistry.
Analytical Chemistry.
Online Access:https://doi.org/10.1007/978-3-540-69039-9
Table of Contents:
  • Macrolide-Based Microtubule-Stabilizing Agents - Chemistry and Structure-Activity Relationships
  • The Chemical Synthesis of Discodermolide
  • The Interaction of Microtubules with Stabilizers Characterized at Biochemical and Structural Levels
  • The Tubulin Binding Mode of MT Stabilizing and Destabilizing Agents Studied by NMR
  • The Tubulin Binding Mode of Microtubule Stabilizing Agents Studied by Electron Crystallography
  • Microtubule-Destabilizing Agents: Structural and Mechanistic Insights from the Interaction of Colchicine and Vinblastine with Tubulin
  • Molecular Modeling Approaches to Study the Binding Mode on Tubulin of Microtubule Destabilizing and Stabilizing Agents.

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