The Treatment of Mycosis with Imidazole Derivatives
| Autor principal: | |
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| Autor Corporativo: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
1980.
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| Edición: | 1st ed. 1980. |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/978-3-642-67508-9 |
Tabla de Contenidos:
- 1 Introduction
- 1.1 Antimicrobial Therapy
- 1.2 Microbial Diseases of the Skin and Mucous Membranes
- 1.3 Antimicrobial Drugs for Local Application
- 2 Broad-Spectrum Antimicrobials for Local Application
- 2.1 Preliminary Remarks
- 2.2 Disinf ectants and Antiseptics
- 2.3 Antibiotics
- 2.4 Chemotherapeutic Agents
- 2.5 Imidazole Derivatives with Antimicrobial Action
- 3 Econazole
- 3.1 General
- 3.2 Chemical Structure
- 3.3 Physical Properties
- 3.4 Antimicrobial Spectrum
- 4 General Microbiology of Imidazole Derivatives for Local Application
- 4.1 Preliminary Remarks
- 4.2 Modeof Action
- 4.3 Resistance and Tolerance
- 4.4 Interactions with Other Compounds
- 4.5 Bioavailability Studies
- 5 Therapeutic Use of Imidazole Derivatives in Animals (Experimental Therapy)
- 5.1 Local Application
- 5.2 Systemic Application
- 6 General Pharmacology of the Imidazole Derivatives in Man and Animals
- 6.1 Pharmacologic Properties (Apart from Antimicrobial Action) ..
- 6.2 Absorption, Excretion, and Metabolism in Animals
- 6.3 Absorption, Excretion, and Metabolism in Man
- 6.4 Sensitization
- 6.5 Anaphylactoid Activity
- 7 Toxicology of the Imidazole Derivatives
- 7.1 Preliminary Remarks
- 7.2 SystemicToxicity
- 7.3 LocalToxicity
- 8 Clinical Pharmacology of Topical Antimicrobials with Special Regard to the Imidazole Derivatives
- 8.1 Preliminary Remarks
- 8.2 Physical Properties
- 8.3 SkinTolerance
- 8.4 Sensitization
- 8.5 Photosensitizing Reactions
- 8.6 Interactions with Substances on the Skin Surface
- 8.7 Penetration and Absorption
- 8.8 Systemic Administration
- 8.9 Use in Veterinary Mediane and the Food Industry
- 8.10 Special Clinical Pharmacologic Considerations in the Local Application of Antimicrobials
- 8.11 Clinical Pharmacology of the Preparation
- 9 Microbial Infections in Man
- 9.1 General
- 9.2 Increase in Microbial Infections of Body Surfaces
- 9.3 Saprophytes and Parasites on Body Surf aces
- 9.4 Mixed and Double Inf ections of Body Surf aces
- 10 Mycoses
- 10.1 Etiology of Mycoses
- 10.2 The Increase in Mycoses
- 10.3 Classification of Mycoses
- 10.4 Mycoses of the Skin and Mucous Membranes
- 10.5 Mycoses of the Female Genitalia
- 10.6 Systemic Mycoses
- 10.7 General Principles in the Treatment of Mycoses
- 11 Systemic Administration of Antimycotically Active Imidazole Derivatives in Man
- 12 Local Application of Antimycotically Active Imidazole Derivatives in Man
- 12.1 Application to the Outer Skin
- 12.2 Application to the Mucous Membranes
- 13 Combined Use of Imidazole Derivatives and Glucocortoids for the Local Treatment of Skin Diseases
- 13.1 Preliminary Remarks
- 13.2 Combination of Antibiotics with Glucocortoids
- 13.3 Salicylic Acid, Haloprogin, Clioquinol, Chlorquinaldol, and Triclosan
- 13.4 Imidazole Derivatives and Glucocortoids
- 13.5 Indications for the Combined Use of Imidazole Derivatives and Glucocorticoids
- 14 Assessment of Mycoses in Various Branches of Mediane
- 14.1 Dermatology
- 14.2 Gynecology
- 14.3 Pediatrics
- 14.4 Stomatology
- 14.5 Otolaryngology
- 14.6 Otorhinolaryngology
- 14.7 Proctology
- 14.8 Urology
- 14.9 Internal Mediane
- 14.10 Orthopedics
- 14.11 Surgery, Intensive Care, Anesthesiology
- 15 Concluding Remarks
- 16 References
- 17 Subject Index.