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03912nam a22003255i 4500 |
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978-4-431-34200-7 |
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20191024043506.0 |
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cr nn 008mamaa |
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100301s2006 ja | s |||| 0|eng d |
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|a 9784431342007
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| 024 |
7 |
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|a 10.1007/4-431-34200-1
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Sphingolipid Biology
|c edited by Y. Hirabayashi, Y. Igarashi, A.H. Jr. Merrill.
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| 250 |
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|a 1st ed. 2006.
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| 260 |
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|a Tokyo :
|b Springer Japan :
|b Imprint: Springer,
|c 2006.
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| 300 |
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|a XXV, 531 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Overview -- Sphingolipids Synthesis, Transport and Cellular Signaling -- Biosynthesis, Transport of Sphingolipids -- Serine Palmitoyltransferase -- Ceramide Synthase -- Dihydroceramide: Sphinganine ?4-Desaturase and C4-Hydroxylase -- Metabolizing Enzymes Such As Sphingomyelin Synthase Induce Cell Death by Increasing Ceramide Content -- Glucosylceramide and Galactosylceramide Synthase -- Synthesis, Metabolism, and Trans-Bilayer Movement of Long-Chain Base -- Molecular Mechanism of Ceramide Trafficking from the Endoplasmic Reticulum to the Golgi Apparatus in Mammalian Cells -- Sphingolipid Trafficking -- Current Perspectives on Saccharomyces cerevisiae Sphingolipids -- Generation and Degradation of Sphingolipid Signaling Molecules -- Generation of Signaling Molecules by De Novo Sphingolipid Synthesis -- Overview of Acid and Neutral Sphingomyelinases in Cell Signaling -- Neutral Ceramidase as an Integral Modulator for the Generation of S1P and S1P-Mediated Signaling -- Activation of Sphingosine Kinase 1 -- Ceramide 1-Phosphate -- Sphingosine-1-Phosphate Lyase -- Membrane Domain and Biological Function -- Close Interrelationship of Sphingomyelinase and Caveolin in Triton X-100-lnsoluble Membrane Microdomains -- Roles of Membrane Domains in the Signaling Pathway for B Cell Survival -- The Role of Lipid Rafts in Axon Growth and Guidance -- Sphingolipids and Multidrug Resistance of Cancer Cells -- Membrane Lipid Domain and Human Pathobiology -- A New Pathological Feature of Insulin Resistance and Type 2 Diabetes: Involvement of Ganglioside GM3 and Membrane Microdomains -- Neuronal Cell Death in Glycosphingolipidoses -- Endocytic Trafficking of Glycosphingolipids in Sphingolipidoses -- Ganglioside and Alzheimer's Disease -- Modulation of Proteolytic Processing by Glycosphingolipids Generates Amyloid ?-Peptide -- Hereditary Sensory Neuropathy -- Ceramide, Ceramide Kinase and Vision Defects: A BLIND Spot for LIPIDS -- Fumonisin Inhibition of Ceramide Synthase: A Possible Risk Factor for Human Neural Tube Defects -- Sphingolipids and Cancer -- S1P Signaling and SIPR -- Sphingosine-1-Phosphate and the Regulation of Immune Cell Trafficking -- Sphingolipids and Lung Vascular Barrier Regulation -- Signaling Mechanisms for Positive and Negative Regulation of Cell Motility by Sphingosine-1-Phosphate Receptors -- Sphingosine 1-Phosphate-Related Metabolism in the Blood Vessel -- Advanced Technology in Sphingolipid Biology -- Conventional/Conditional Knockout Mice -- Biosynthesis and Function of Drosophila Glycosphingolipids -- Characterization of Genes Conferring Resistance Against ISP-1/Myriocin-Induced Sphingolipid Depletion in Yeast -- Lysenin: A New Probe for Sphingomyelin -- Structural Biology of Sphingolipid Synthesis -- A Computer Visualization Model for the De Novo Sphingolipid Biosynthetic Pathway.
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| 650 |
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|a Cell biology.
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| 650 |
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0 |
|a Biochemistry.
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| 650 |
1 |
4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Biochemistry, general.
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| 700 |
1 |
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|a Hirabayashi, Y.
|e editor.
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| 700 |
1 |
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|a Igarashi, Y.
|e editor.
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| 700 |
1 |
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|a Merrill, A.H. Jr.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/4-431-34200-1
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