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02516nam a22003615i 4500 |
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978-4-431-75452-7 |
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20191025141925.0 |
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cr nn 008mamaa |
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100301s2008 ja | s |||| 0|eng d |
| 020 |
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|a 9784431754527
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| 024 |
7 |
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|a 10.1007/978-4-431-75452-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Pancreatic Beta Cell in Health and Disease
|c edited by Susumu Seino, Graeme I. Bell.
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| 250 |
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|a 1st ed. 2008.
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| 260 |
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|a Tokyo :
|b Springer Japan :
|b Imprint: Springer,
|c 2008.
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| 300 |
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|a XV, 476 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Pancreatic Beta Cell and Insulin Biosynthesis -- Architecture of Pancreatic Islets -- Transcriptional Regulation of Insulin Gene Expression -- The Biosynthesis of Insulin -- Cell Signaling and Insulin Secretion -- Metabolic Regulation of Insulin Secretion -- Mechanisms of Beta-Cell Death in Diabetes -- Ion Channels and Insulin Secretion -- Gap Junctions and Insulin Secretion -- Protein Kinase A-Independent Mechanism of cAMP in Insulin Secretion -- Regulation of Insulin Granule Exocytosis -- Mechanism of Insulin Exocytosis Analyzed by Imaging Techniques -- Two-Photon Excitation Imaging of Insulin Exocytosis -- Pancreatic Development and Beta-Cell Formation -- Regulation of Beta-Cell Growth and Death -- Beta-Cell Replication -- Stem Cells as a Cure for Diabetes -- Use of Extra-Pancreatic Tissues for Cell Replacement Therapy for Diabetes -- Incretins and Beta-Cell Function -- Molecular Biology of Gluco-Incretin Function -- Incretins and Regulation of Insulin Secretion -- Pancreatic Beta Cell and Disease -- Pancreatic Islet Pathology in Type 2 Diabetes -- Genetic Disorders of the Pancreatic Beta Cell and Diabetes (Permanent Neonatal Diabetes and Maturity-Onset Diabetes of the Young) -- ATP-Sensitive Potassium Channels in Health and Disease -- Glucokinase in Glucose Homeostasis, Diabetes Mellitus, Hypoglycemia, and as Drug Receptor.
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| 650 |
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0 |
|a Cell biology.
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| 650 |
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0 |
|a Diabetes.
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| 650 |
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0 |
|a Molecular biology.
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| 650 |
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0 |
|a Internal medicine.
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| 650 |
1 |
4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Diabetes.
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| 650 |
2 |
4 |
|a Molecular Medicine.
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| 650 |
2 |
4 |
|a Internal Medicine.
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| 700 |
1 |
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|a Seino, Susumu.
|e editor.
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| 700 |
1 |
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|a Bell, Graeme I.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-4-431-75452-7
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