The DNA Damage Response: Implications on Cancer Formation and Treatment

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Khanna, Kum Kum. (Editor ), Shiloh, Yosef. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2009.
Edición:1st ed. 2009.
Materias:
Acceso en línea:https://doi.org/10.1007/978-90-481-2561-6
Tabla de Contenidos:
  • DNA Damage Sensing and Signaling
  • Signaling at Stalled Replication Forks
  • An Oncogene-Induced DNA Replication Stress Model for Cancer Development
  • Cellular Responses to Oxidative Stress
  • Cell Cycle Regulation and DNA Damage
  • Chromatin Modifications Involved in the DNA Damage Response to Double Strand Breaks
  • Telomere Metabolism and DNA Damage Response
  • DNA Double Strand Break Repair: Mechanisms and Therapeutic Potential
  • DNA Base Excision Repair: A Recipe for Survival
  • DNA Damage Tolerance and Translesion Synthesis
  • Nucleotide Excision Repair: from DNA Damage Processing to Human Disease
  • Chromosomal Single-Strand Break Repair
  • Mouse Models of DNA Double Strand Break Repair Deficiency and Cancer
  • Cancer Biomarkers Associated with Damage Response Genes
  • Linking Human RecQ Helicases to DNA Damage Response and Aging
  • Single-Stranded DNA Binding Proteins Involved in Genome Maintenance
  • The Fanconi anemia-BRCA Pathway and Cancer
  • BRCA1 and BRCA2: Role in the DNA Damage Response, Cancer Formation and Treatment.