DNA-Protein Interactions
| Autor principal: | |
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| Autor Corporativo: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Dordrecht :
Springer Netherlands : Imprint: Springer,
1993.
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| Edición: | 1st ed. 1993. |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/978-94-011-1480-6 |
Tabla de Contenidos:
- 1 DNA structure
- 1.1 Structural features of DNA
- 1.2 DNA polymorphism
- 1.3 Conformational variability of DNA
- 1.4 Intrinsic bending of DNA
- 1.5 DNA supercoiling and topology
- 1.6 The topology of protein-bound DNA
- 1.7 Structure of supercoiled DNA
- References
- 2 DNA-protein interactions: The three-dimensional architecture of DNA-protein complexes
- 2.1 General principles
- 2.2 Local DNA conformation and protein binding
- 2.3 DNA wrapping
- 2.4 DNA configuration and sequence periodicity
- 2.5 The establishment of DNA architecture
- References
- 3 DNA-protein interactions: Sequence specific recognition
- 3.1 General principles of sequence specific recognition
- 3.2 Structural motifs for sequence specific binding
- 3.3 Co-operative binding to DNA
- 3.4 Co-operativity at a distance: DNA looping
- 3.5 Protein flexibility in DNA-protein complexes
- References
- 4 The mechanism of RNA chain initiation
- 4.1 The promoter
- 4.2 RNA polymerases
- 4.3 The kinetics of transcription initiation
- 4.4 The molecular interactions of RNA polymerase with a promoter site
- 4.5 The topological consequences of transcription
- 4.6 Transcriptional activators
- 4.7 Transcriptional activation by negative superhelicity
- 4.8 How does RNA polymerase melt promoter DNA?
- References
- 5 The regulation of promoter selectivity in eubacteria
- 5.1 Control of stable RNA synthesis
- 5.2 Stable RNA promoters
- 5.3 The transition from exponential growth to stationary phase and vice versa
- 5.4 Sigma factors and promoter recognition
- 5.5 The heat shock response
- 5.6 ?54: A target for transcriptional enhancers
- 5.7 The transcriptional programmes of bacterial viruses
- References
- 6 The mechanism of eukaryotic transcription
- 6.1 Eukaryotic transcriptional regulatory elements
- 6.2 Eukaryotic transcriptional regulators: structure
- 6.3 Specificity and selectivity of eukaryotic transcription factors
- 6.4 Sp1 transcription factor
- 6.5 Heat shock transcription factor (HSF)
- 6.6 How do transcriptional activators work?
- 6.7 Transcription by RNA polymerase III
- 6.8 The establishment of repression
- References
- 7 Chromatin and transcription
- 7.1 Local control of chromatin structure
- 7.2 The structural organization of chromatin
- 7.2.1 Chromosomal superstructure
- 7.3 Heterochromatin
- 7.4 The regulation of transcriptional competence
- References.