Novel T cell receptors reactive to the HPV16 E6 and E7 oncoproteins and strategy to potentiate their signaling strength using a co-stimulatory chimeric antigen receptor /

More than 95% of all cervical cancer cases worldwide are caused by high-risk human papillomaviruses (HPV). The transformation and survival of the malignant HPV+ cells depend on the expression of the viral E6 and E7 oncoproteins, which makes them appropriate tumor-specific targets for immunotherapy....

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Detalles Bibliográficos
Autor principal: Quirós Fernández, Isaac 1993- (Autor/a)
Formato: Tesis Libro
Lenguaje:English
Publicado: Heidelberg, [Alemania], 2023.
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