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03997nam a22003135i 4500 |
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cr nn 008mamaa |
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180609s2018 xxu| s |||| 0|eng d |
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|a 9781493978168
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| 024 |
7 |
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|a 10.1007/978-1-4939-7816-8
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Amyloid Proteins :
|b Methods and Protocols /
|c edited by Einar M. Sigurdsson, Miguel Calero, María Gasset.
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| 250 |
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|a 3rd ed. 2018.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2018.
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| 300 |
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|a XVII, 547 p. 99 illus., 65 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1779
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| 505 |
0 |
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|a Preparation of Pure Populations of Amyloid-β Protein Oligomers of Defined Size -- Preparation of Well-Defined and Stable β-Barrel Pore-Forming Amyloid-β42 Oligomers -- Unveiling Brain Aβ Heterogeneity through Targeted Proteomic Analysis -- Preparation of α-Synuclein Amyloid Assemblies for Toxicity Experiments -- Generation and Characterization of Stable α-Synuclein Oligomers -- In Vitro Analysis of α-Synuclein Amyloid Formation and Cross-Reactivity -- Preparation of Tau Oligomers after Protein Extraction from Bacteria and Brain Cortices -- Purification and Characterization of Low-n Tau Oligomers -- Preparation and Characterization of Tau Oligomer Strains -- Purification and Fibrillation of Recombinant Human Amyloid-β, Prion Protein and Tau under Native Conditions -- Preparation of Amyloidogenic Aggregates from EF-Hand β –parvalbumin and S100 Proteins -- Kinetic Analysis of Amyloid Formation -- Mapping Amyloid Regions in Gad m 1 with Peptide Arrays -- Non-Invasive Structural Analysis of Intermediate Species during Fibrillation: An Application of Small-Angle X-Ray Scattering -- Analysis of Covalent Modifications of Amyloidogenic Proteins using Two-Dimensional Electrophoresis: Prion Protein and Its Sialylation -- Amplification and Detection of Minuscule Amounts of Misfolded Prion Protein by Using The Real-Time Quaking-Induced-Conversion -- Bacterial Amyloids -- Addressing Intracellular Amyloidosis in Bacteria with RepA-WH1, a Prion-Like Protein -- Study of Amyloids Using Yeast -- Neurotoxic Ca2+ Signaling Induced by Amyloid-β Oligomers in Aged Hippocampal Neurons In Vitro -- Preparation and Culturing of Human Primary Vascular Cells -- Live Imaging of Pathological Tau Protein and Tau Antibodies in a Human Neuron-Like Cellular Model -- Effects of Amyloid-β Peptide on the Biology of Human Neural Stem Cells -- Development of Mouse Monoclonal Antibodies against Human Amyloid Fibril Proteins for Diagnostic and Research Purposes -- Identification and Characterization of Amyloid-β Accumulation in Synaptic Mitochondria -- Biochemical Properties of Pathology-Related Tau Species in Tauopathy Brains: An Extraction Protocol for Tau Oligomers and Aggregates -- Tau Assembly into Filaments -- Quantitative Metabolomics in Alzheimer´s Disease: Technical Considerations for Improved Reproducibility -- Detecting Circulating MicroRNAs as Biomarkers in Alzheimer’s Disease -- Luminescent Conjugated Oligothiophene Probe Applications for Fluorescence Imaging of Pure Amyloid Fibrils and Protein Aggregates in Tissues -- Characterization of Amyloid-β Plaques and Autofluorescent Lipofuscin Aggregates in Alzheimer´s Disease Brain: A Confocal Microscopy Approach -- In Vivo Imaging of Tauopathy in Mice -- In Vivo Evaluation of Neuronal Transport in Murine Models of Neurodegeneration using Manganese-Enhanced MRI.
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| 650 |
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|a Proteins .
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| 650 |
1 |
4 |
|a Protein Science.
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| 700 |
1 |
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|a Sigurdsson, Einar M.
|e editor.
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| 700 |
1 |
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|a Calero, Miguel.
|e editor.
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| 700 |
1 |
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|a Gasset, María.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|