Alpha-Synuclein : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Bartels, Tim. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2019.
Edición:1st ed. 2019.
Colección:Methods in Molecular Biology, 1948
Materias:
Tabla de Contenidos:
  • Assays for Neuronal Defects Caused by Early Formation of α-Synuclein Inclusions in Primary Cultured Neurons
  • Immunohistochemical Detection of Alpha-Synuclein in Unfixed Human Brain Tissue
  • Kinetic Measurements of Endocytosis and Exocytosis in Cultured Neurons
  • Detection of Misfolded α-Synuclein Aggregates in Cerebrospinal Fluid by the Protein Misfolding Cyclic Amplification Platform
  • Stereotaxic Targeting of Alpha-Synuclein Pathology in Mouse Brain using Pre-Formed Fibrils
  • Quantification of Alpha-Synuclein in Biological Fluids by Electrochemiluminescence-Based Detection
  • Alpha-Synuclein Proximity Ligation Assay (AS-PLA) in Brain Sections to Probe for Alpha-Synuclein Oligomers
  • Studying α-Synuclein Conformation by Intact-Cell Crosslinking
  • C. elegans as a Model for Synucleinopathies and Other Neurodegenerative Diseases: Tools and Techniques
  • Recombinant Expression and Purification of N-Acetylated Alpha-Synuclein
  • Circular Dichroism and Isothermal Titration Calorimetry to Study the Interaction of α-Synuclein with Membranes
  • Yeast-Based Screens to Target Alpha-Synuclein Toxicity
  • Probing Structural Changes in Alpha Synuclein by Nuclear Magnetic Resonance Spectroscopy
  • Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers
  • Monitoring α-Synuclein Proteotoxicity in Drosophila Models
  • Detection of α-Synuclein in Biological Samples using Mass Spectrometry
  • Single-Molecule FRET Detection of Early-Stage Conformations in α-Synuclein Aggregation
  • In Situ Peroxidase Labelling and Mass-Spectrometry of Alpha-Synuclein in Rat Cortical Neurons
  • Probing Alpha-Synuclein Conformations by Electron Paramagnetic Resonance (EPR) Spectroscopy
  • Expression and Purification of Untagged α-Synuclein
  • Generation and Analysis of Viral Vector Mediated Rodent Models for Parkinson’s Disease.