Biomarkers for Immunotherapy of Cancer : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Thurin, Magdalena. (Editor ), Cesano, Alessandra. (Editor ), Marincola, Francesco M. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2020.
Edición:1st ed. 2020.
Colección:Methods in Molecular Biology, 2055
Materias:
Tabla de Contenidos:
  • Status of Immune-oncology: Challenges and Opportunities
  • Immunological Targets for Immunotherapy: Inhibitory T Cell Receptors
  • Measuring Tumor Mutational Burden Using Whole Exome Sequencing
  • Germline Genetics in Immuno-Oncology: From Genome-wide to Targeted Biomarker Strategies
  • Detection of Microsatellite Instability Biomarkers via Next-generation Sequencing
  • Genetic Instability Markers in Cancer
  • Validation of Circulating Tumor DNA Assays for Detection of Metastatic Melanoma
  • Techniques Associated with Exosome Isolation for Biomarker Development – Liquid Biopsies for Ovarian Cancer Detection
  • Identifying MicroRNA Pathway Variants as Biomarkers of Patient Selection for Immune Therapy
  • Histone Modifications as Biomarkers for Immunotherapy
  • Functional Genome Profiling to Understand Cancer Immune Responsiveness
  • Using RNA-sequencing to Characterize the Tumor Microenvironment
  • Development of Gene Expression Based Biomarkers on the nCounter® Platform for Immuno-Oncology Applications
  • The CRISPR System and Cancer Immunotherapy Biomarkers
  • HLA Class I Antigen Processing Machinery Defects in Cancer Cells - Frequency, Functional Significance and Clinical Relevance with Special Emphasis on their Role in T cell-based Immunotherapy of Malignant Disease
  • High-parameter Immune Profiling with CyTOF
  • The Adaptome as Biomarker for Assessing Cancer Immunity and Immunotherapy
  • Single Molecule Arrays for Ultrasensitive Detection of Blood-based Biomarkers for Immunotherapy
  • Single-cell Multiplexed Proteomics on the IsoLight Resolves Cellular Functional Heterogeneity to Reveal Clinical Responses of Cancer Patients to Immunotherapies
  • Methods to Detect Immunogenic Cell Death in vivo
  • Overview of Tissue Imaging Methods
  • Multiplex Immunofluorescence Assays
  • Multiplexed Immunohistochemical Consecutive Staining on Single Slide (MICSSS): Multiplexed Chromogenic IHC Assay for High-Dimensional Tissue Analysis
  • Cyclic Multiplexed-Immunofluorescence (cmIF), A Highly Multiplexed Method for Single-cell Analysis
  • High-Plex Spatially Resolved RNA and Protein Detection using Digital Spatial Profiling: A Technology Designed for Immuno-Oncology Biomarker Discovery and Translational Research
  • The InSituPlex® Staining Method for Multiplexed Immunofluorescence Cell Phenotyping and Spatial Profiling of Tumor FFPE Samples
  • Microbiome as an Immunological Modifier
  • Systems Biology for Multi-Platform Data Integration – Overview
  • Bioinformatics Tools and Resources for Cancer Immunotherapy Study
  • Multiplatform Integrative Analysis of Immunogenomic Data for Biomarker Discovery
  • Translating Immuno-Oncology Biomarkers to Diagnostic tests: A regulatory Perspective.