Biomolecular Interfaces : Interactions, Functions and Drug Design /
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| Autor Corporativo: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edición: | 1st ed. 2015. |
| Materias: |
Tabla de Contenidos:
- The Aqueous Interface of a Soluble Protein or the Birth of Epistructural Biology
- Electrostatic Exploration of Biomolecular Interfaces: The Chemical Function of Interfacial Water
- Semiempirical Solution to the Protein Folding Problem Through a Combination of Structural and Epistructural Approaches
- Packing Defects and Protein Hydration: Dynamics of the Aqueous Interface
- Proteins in the Order-Disorder Twilight: Unstable Interfaces Promote Protein Aggregation
- Evolution of Protein Structure Degradation and Lessons for the Drug Designer
- Chemical Functionality of the Aqueous Interface in Soluble Proteins
- The Biomolecular Interface as a Selectivity Filter for Drug-Based Targeted Therapy
- Wrapping-Based Re-Engineering of an Anticancer Drug to Make it Safer
- Biomolecular Interfaces Provide Universal Markers for Drug Specificity and Personalized Medicine
- Controlling Induced Folding Through Wrapping Drug Design
- Wrapping Drug Combinations for Therapeutic Editing of Side Effects: Systems Biology Meets Wrapping Technology
- Multi-Target Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology
- Engineering Therapeutic Alignments between Immune Response and Molecularly Targeted Cancer Treatment
- High-Level Quantum Chemistry Empowers the Wrapping Technology for Drug Design
- Epilogue
- Appendix 1. Code for Dehydron Identification
- Appendix 2. Solutions of Problems.