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100301s2010 xxu| s |||| 0|eng d |
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|a 9781441910752
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| 024 |
7 |
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|a 10.1007/978-1-4419-1075-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Cellular Senescence and Tumor Suppression /
|c edited by Peter D. Adams, John M. Sedivy.
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| 250 |
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|a 1st ed. 2010.
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| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2010.
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| 300 |
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|a XIII, 272 p. With 1 4-color insert. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Senescence signals -- Telomere Biology and Biochemistry -- Role of RecQ Helicases in Nuclear DNA Repair and Telomere Maintenance -- Oncogene-Induced Senescence (OIS) as a Cellular Response to Oncogenic Stresses -- Stress-Induced Senescence -- The senescent phenotype -- The Secretome of Senescent Cells -- Chromatin Structure in Senescent Cells -- A Comparison of Senescence in Mouse and Human Cells -- The physiological consequences of senescence -- Replicative Senescence as an Intrinsic Tumor-Suppressor Mechanism -- Telomere Dysfunction and Senescence in Stem Cell and Tissues Aging -- Mining Cellular Senescence for Drug Targets.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Human genetics.
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| 650 |
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|a Pharmacology.
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| 650 |
1 |
4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Human Genetics.
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| 650 |
2 |
4 |
|a Pharmacology/Toxicology.
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| 700 |
1 |
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|a Adams, Peter D.
|e editor.
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| 700 |
1 |
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|a Sedivy, John M.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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