Cellular Senescence and Tumor Suppression /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Adams, Peter D. (Editor ), Sedivy, John M. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Materias:
Tabla de Contenidos:
  • Senescence signals
  • Telomere Biology and Biochemistry
  • Role of RecQ Helicases in Nuclear DNA Repair and Telomere Maintenance
  • Oncogene-Induced Senescence (OIS) as a Cellular Response to Oncogenic Stresses
  • Stress-Induced Senescence
  • The senescent phenotype
  • The Secretome of Senescent Cells
  • Chromatin Structure in Senescent Cells
  • A Comparison of Senescence in Mouse and Human Cells
  • The physiological consequences of senescence
  • Replicative Senescence as an Intrinsic Tumor-Suppressor Mechanism
  • Telomere Dysfunction and Senescence in Stem Cell and Tissues Aging
  • Mining Cellular Senescence for Drug Targets.