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02551nam a22002895i 4500 |
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100301s2002 xxu| s |||| 0|eng d |
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|a 9781592592852
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024 |
7 |
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|a 10.1385/1592592856
|2 doi
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040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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245 |
1 |
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|a Combinatorial Library :
|b Methods and Protocols /
|c edited by Lisa B. English.
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250 |
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|a 1st ed. 2002.
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260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2002.
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300 |
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|a XI, 383 p. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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337 |
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Methods in Molecular Biology,
|v 201
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505 |
0 |
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|a Library Synthesis and Quality Control -- Using a Noncovalent Protection Strategy to Enhance Solid-Phase Synthesis -- Quality Control of Solid-Phase Synthesis by Mass Spectrometry -- Preparation of Encoded Combinatorial Libraries for Drug Discovery -- Simple Tools for Manual Parallel Solid Phase Synthesis -- Cleavage of Compounds from Solid Phase by Gaseous Reagents -- Synthesis of DNA-Binding Polyamides -- The Preparation of Phenyl-stilbene Derivatives Using the Safety Catch Linker -- Host—Guest Chemistry -- Automated Structure Verification of Small Molecules Libraries Using 1D and 2D NMR Techniques -- Rapid Liquid-Phase Combinatorial Synthesis of Heterocyclic Libraries -- Soluble Polymer-Supported Methods for Combinatorial and Organic Synthesis -- Analytical Methods for Optimization and Quality Control of Combinatorial Synthesis -- Library Purification and Screening -- Resolving Racemic Mixtures Using Parallel Combinatorial Libraries -- Ligand Libraries for the Extraction of Metal Ions -- Automated Liquid-Liquid Extraction and Ion-Exchange Solid-Phase Extraction for Initial Purification -- On-Bead and Solution Screening Approaches for Genomically Derived Targets -- Computational Library Design -- Design of Virtual Combinatorial Libraries -- Approaches to Library Design for Combinatorial Chemistry -- Reagent-Based and Product-Based Computational Strategies in Library Design -- Designing Combinatorial Libraries for Efficient Screening -- Application of Neural Networks to Large Dataset QSAR, Virtual Screening, and Library Design.
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650 |
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|a Biochemistry.
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650 |
1 |
4 |
|a Biochemistry, general.
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700 |
1 |
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|a English, Lisa B.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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