Combinatorial Library : Methods and Protocols /
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| Format: | eBook |
| Language: | English |
| Published: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2002.
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| Edition: | 1st ed. 2002. |
| Series: | Methods in Molecular Biology,
201 |
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Table of Contents:
- Library Synthesis and Quality Control
- Using a Noncovalent Protection Strategy to Enhance Solid-Phase Synthesis
- Quality Control of Solid-Phase Synthesis by Mass Spectrometry
- Preparation of Encoded Combinatorial Libraries for Drug Discovery
- Simple Tools for Manual Parallel Solid Phase Synthesis
- Cleavage of Compounds from Solid Phase by Gaseous Reagents
- Synthesis of DNA-Binding Polyamides
- The Preparation of Phenyl-stilbene Derivatives Using the Safety Catch Linker
- Host-Guest Chemistry
- Automated Structure Verification of Small Molecules Libraries Using 1D and 2D NMR Techniques
- Rapid Liquid-Phase Combinatorial Synthesis of Heterocyclic Libraries
- Soluble Polymer-Supported Methods for Combinatorial and Organic Synthesis
- Analytical Methods for Optimization and Quality Control of Combinatorial Synthesis
- Library Purification and Screening
- Resolving Racemic Mixtures Using Parallel Combinatorial Libraries
- Ligand Libraries for the Extraction of Metal Ions
- Automated Liquid-Liquid Extraction and Ion-Exchange Solid-Phase Extraction for Initial Purification
- On-Bead and Solution Screening Approaches for Genomically Derived Targets
- Computational Library Design
- Design of Virtual Combinatorial Libraries
- Approaches to Library Design for Combinatorial Chemistry
- Reagent-Based and Product-Based Computational Strategies in Library Design
- Designing Combinatorial Libraries for Efficient Screening
- Application of Neural Networks to Large Dataset QSAR, Virtual Screening, and Library Design.