From Molecular to Modular Tumor Therapy : Tumors are Reconstructible Communicatively Evolving Systems /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Reichle, Albrecht. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Colección:The Tumor Microenvironment ; 3
Materias:
Tabla de Contenidos:
  • Therapy-Derived Systems Biology: A Pragmatic Communication Theory
  • Bridging Theory and Therapeutic Practice: From Generalized Disease Models to Particular Patients
  • Tumor Systems Need to be Rendered Usable for a New Action-Theoretical Abstraction: The Starting Point for Novel Therapeutic Options
  • Principles of Modular Tumor Therapy
  • Tumors Share Common Processes During Tumor Evolution: Communicative Aspects of a Situation’s Interpretation for Creating Systems-Directed Therapies
  • Cancer and Coagulation; Focusing on Tissue Factor and Heparanase
  • The Role of Mesenchymal Cells in Cancer: Contribution to Tumor Stroma and Tumorigenic Capacity
  • Shaping Tumor Associated Macrophages: The Role of NF-?B
  • The Metabolic Achilles Heel: Tumor Cell Metabolism as Therapeutic Target
  • Could Be Systems-Directed Therapy Approaches Promising in Glioblastoma Patients?
  • Systems-Relevant Molecular and Cellular Targets: Implementation of Modular ‘Knowledge’
  • Functional Impacts of Signal Integration: Regulation of Inflammation-Related Transcription Factors by Heterotrimeric G Proteins
  • Molecular Cross-Talk Between Nuclear Receptors and Nuclear Factor-?B
  • The Biomodulatory Capacities of Low-Dose Metronomic Chemotherapy: Complex Modulation of the Tumor Microenvironment
  • Tumors are Evolvable Modular and Rationalized Systems: From Molecular to Modular Tumor Therapy
  • Systems Biology: A Therapeutic Target for Tumor Therapy
  • The Comparative Uncovering of Tumor Systems Biology by Modularly Targeting Tumor-Associated Inflammation
  • Searching for the ‘Metabolism’ of Evolution
  • Biomodulatory Therapy Approaches in Metastatic Cancer
  • The Impact of Inflammation Control and Active Cancer Palliation on Metabolic Pathways Determining Tumor Progression and Patient Survival
  • Pioglitazone and Rofecoxib Combined with Angiostatically Scheduled Capecitabine in Far-Advanced Hepatobiliary Carcinoma
  • C-Reactive Protein As a Secretome-Derived Biomarker for Predicting Response to Biomodulatory Therapy in Metastatic Renal Clear Cell Carcinoma
  • Modular Therapy Approach in Metastatic Castration-Resistent Prostate Cancer
  • Systems-Directed Therapy in Metastatic Castration-Resistent Prostate Cancer (CRCP)
  • Criteria for Checking Systems Behavior and Creating Predictions: Systems-Associated Biomarkers and Molecular Imaging
  • Early Detection of Systems Response: Molecular and Functional Imaging of Angiogenesis
  • Secretome Proteomics, a Novel Tool for Biomarkers Discovery and for Guiding Biomodulatory Therapy Approaches
  • Cyclooxygenase 2 (COX2) and Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Are Stage-Dependent Prognostic Markers of Malignant Melanoma
  • Pharmacological Considerations on Systems Biological Therapy Approaches
  • Uncovering Tumor Systems Biology by Biomodulatory Therapy Strategies
  • Breathing New Life into Old Drugs: Indication Discovery by Systems Directed Therapy
  • Tumors’ Systems Biology: Implications for Personalized Therapy
  • A Methodological Approach to Personalized Therapies in Metastatic Cancer
  • Summary
  • To Be an Object in a Biological System
  • From Molecular to Modular, from Theme-Dependent to Evolution-Adjusted Tumor Therapy.