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20200929155752.0 |
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cr nn 008mamaa |
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181008s2019 xxu| s |||| 0|eng d |
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|a 9781493987368
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| 024 |
7 |
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|a 10.1007/978-1-4939-8736-8
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Computational Methods in Protein Evolution /
|c edited by Tobias Sikosek.
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| 250 |
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|a 1st ed. 2019.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2019.
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| 300 |
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|a XIII, 420 p. 103 illus., 80 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1851
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| 505 |
0 |
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|a Predicting the Effect of Mutations on Protein Folding and Protein-Protein Interactions -- Accurate Calculation of Free Energy Changes Upon Amino Acid Mutation -- Protocols for the Molecular Evolutionary Analysis of Membrane Protein Gene Duplicates -- Computational Prediction of De Novo Emerged Protein-Coding Genes -- Coevolutionary Signals and Structure-Based Models for the Prediction of Protein Native Conformations -- Detecting Amino Acid Coevolution with Bayesian Graphical Models -- Context-Dependent Mutation Effects in Proteins -- High-Throughput Reconstruction of Ancestral Protein Sequence, Structure, and Molecular Function -- Ancestral Sequence Reconstruction as a Tool for the Elucidation of a Stepwise Evolutionary Adaptation -- Enhancing Statistical Multiple Sequence Alignment and Tree Inference using Structural Information -- The Influence of Protein Stability on Sequence Evolution: Applications to Phylogenetic Inference -- Navigating Among Known Structures in Protein Space -- A Graph-Based Approach for Detecting Sequence Homology in Highly Diverged Repeat-Protein Families -- Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function -- Identification of Protein Homologs and Domain Boundaries by Iterative Sequence Alignment -- A Roadmap to Domain Based Proteomics -- Modelling of Protein Tertiary and Quaternary Structures Based on Evolutionary Information -- Interface-Based Structural Prediction of Novel Host-Pathogen Interactions -- Predicting Functions of Disordered Proteins with MoRFpred -- Exploring Protein Conformational Diversity -- High-Throughput Antibody Structure Modelling and Design using ABodyBuilder -- In Silico Directed Evolution using CADEE.
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| 650 |
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|a Proteins .
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| 650 |
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|a Protein Science.
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| 700 |
1 |
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|a Sikosek, Tobias.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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