Computational Chemogenomics /
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY :
Springer New York : Imprint: Humana,
2018.
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| Edition: | 1st ed. 2018. |
| Series: | Methods in Molecular Biology,
1825 |
| Subjects: |
Table of Contents:
- A Survey of Web-Based Chemogenomic Data Resources
- Finding Potential Multi-Target Ligands Using PubChem
- Fundamental Bioinformatic and Chemoinformatic Data Processing
- Parsing Compound-Protein Bioactivity Tables
- Impact of Molecular Descriptors on Computational Models
- Physicochemical Property Labels as Molecular Descriptors for Improved Analysis of Compound-Protein and Compound-Compound Networks
- Core Statistical Methods for Chemogenomic Data
- Structure-Based Detection of Orthosteric and Allosteric Pockets at Protein-Protein Interfaces
- Single Binding Pockets versus Allosteric Binding
- Mapping Biological Activities to Different Types of Molecular Scaffolds: Exemplary Application to Protein Kinase Inhibitors
- SAR Matrix Method for Large-Scale Analysis of Compound Structure-Activity Relationships and Exploration of Multi-Target Activity Spaces
- Linear and Kernel Model Construction Methods for Predicting Drug-Target Interactions in a Chemogenomic Framework
- Selection of Informative Examples in Chemogenomic Datasets
- A Platform for Comprehensive Genomic Profiling in Human Cancers and Pharmacogenomics Therapy Selection
- The Future of Computational Chemogenomics.