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02916nam a22003735i 4500 |
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000280364 |
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20211110140110.0 |
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cr nn 008mamaa |
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100301s2005 ne | s |||| 0|eng d |
| 020 |
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|a 9781402041426
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| 024 |
7 |
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|a 10.1007/1-4020-4142-X
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Drug Metabolism :
|b Current Concepts /
|c edited by Mino R. Caira, Corina Ionescu.
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| 250 |
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|a 1st ed. 2005.
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| 260 |
# |
# |
|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2005.
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| 300 |
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|a XIV, 422 p. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Drug Metabolism In Context: Introduction -- Absorption -- Drug Distribution -- Dynamics Of Drug Action -- Drug Clearance -- Dynamics Of Drug Clearance -- Pathways Of Biotransformation – Phase I Reactions: Introduction -- Phase I And Phase Ii Metabolism: General Considerations -- Oxidations Involving The Microsomal Mixed-Function Oxidase System -- Oxidations Involving Other Enzymatic Systems -- Metabolic Reactions Involving Reduction -- Hydrolysis -- Miscellanous Phase I Reactions -- The Fate Of Phase I Reaction Products -- . Pathways Of Biotransformation – Phase I Reactions: Introduction -- Glucuronidation -- Acetylation -- Glutathione Conjugation -- Other Conjugative Reactions -- Concluding Remarks -- Enzymatic Systems Involved In Drug Biotransformation: Ntroduction -- Interaction Between A Drug Substrate And An Enzyme -- Enzyme Systems With Specific Roles -- Final Remarks -- Induction And Inhibition Of Drug-Metabolising Enzymes -- Introduction -- Induction -- Inhibition -- Consequences Of The Above Phenomena -- Dietary And Non-Dietary Factors In Enzyme Induction And Inhibition -- Factors That Influence Drug Biotransformation -- Introduction -- Intrinsic Factors -- Environmental Factors -- Further Observations -- Impact Of Gene Variability On Drug Metabolism -- Introduction -- Basic Principles Of Pharmacogenetics -- Pharmaco-Informatics -- Implications For Third Millennium Medicine -- Drug Interactions And Adverse Reactions: Introduction -- Drug-Drug Interactions -- Interactions Between Drugs And Other Entities -- Adverse Reactions -- Summary -- Strategies For Drug Design -- Introduction -- Pharmacokinetics And Metabolism In Drug Research -- The Role Of Formulation -- Concluding Remarks -- Index.
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| 650 |
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0 |
|a Medicine.
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| 650 |
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0 |
|a Pharmacy.
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| 650 |
|
0 |
|a Medicinal chemistry.
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| 650 |
|
0 |
|a Pharmacology.
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| 650 |
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0 |
|a Molecular biology.
|
| 650 |
1 |
4 |
|a Biomedicine, general.
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| 650 |
2 |
4 |
|a Pharmacy.
|
| 650 |
2 |
4 |
|a Medicinal Chemistry.
|
| 650 |
2 |
4 |
|a Pharmacology/Toxicology.
|
| 650 |
2 |
4 |
|a Molecular Medicine.
|
| 700 |
1 |
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|a Caira, Mino R.
|e editor.
|
| 700 |
1 |
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|a Ionescu, Corina.
|e editor.
|
| 710 |
2 |
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|a SpringerLink (Online service)
|
| 773 |
0 |
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|t Springer eBooks
|