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cr nn 008mamaa |
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100721s2010 xxu| s |||| 0|eng d |
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|a 9781597453646
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| 024 |
7 |
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|a 10.1007/978-1-59745-364-6
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Cyclooxygenases :
|b Methods and Protocols /
|c edited by Samir S. Ayoub, Roderick J. Flower, Michael Seed.
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| 250 |
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|a 1st ed. 2010.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2010.
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| 300 |
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|a X, 218 p. 38 illus. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 644
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| 505 |
0 |
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|a In Vitro Protocols for Studying Expression and Activity of Cyclooxygenase Enzymes and Characterisation of Their Inhibition Patterns -- In Vitro Cyclo-oxygenase Expression and Activity Protocols: Introduction to Part I -- Techniques Used to Study Regulation of Cyclooxygenase-2 Promoter Sites -- Purification of Recombinant Human COX-1 and COX-2 -- Cloning and Expression of Cyclooxygenase-1 and Cyclooxygenase-2 -- Expression of Cyclooxygenase Isoforms in the Baculovirus Expression System -- Peroxidase Active Site Activity Assay -- Study of Inhibitors of the PGH Synthases for which Potency Is Regulated by the Redox State of the Enzymes -- Different Methods for Testing Potential Cyclooxygenase-1 and Cyclooxygenase-2 Inhibitors -- In Vitro Cyclooxygenase Activity Assay in Tissue Homogenates -- Techniques Used to Characterize the Binding of Cyclooxygenase Inhibitors to the Cyclooxygenase Active Site -- In Vitro Assays for Cyclooxygenase Activity and Inhibitor Characterization -- Extraction and Measurement of Prostanoids and Isoprostanes -- Extraction and Measurement of Prostanoids and Isoprostanes: Introduction to Part II -- Prostanoid Extraction and Measurement -- Measurement of 8-Iso-Prostaglandin F2? in Biological Fluids as a Measure of Lipid Peroxidation -- In Vivo Models to Study Involvement of Cyclooxygenase Products in Health and Disease -- In Vivo Models to Study Cyclooxygenase Products in Health and Disease: Introduction to Part III -- Protocols to Assess the Gastrointestinal Side Effects Resulting from Inhibition of Cyclo-Oxygenase Isoforms -- Cyclooxygenase Enzymes and Their Products in the Carrageenan-Induced Pleurisy in Rats -- Iloprost-Induced Nociception: Determination of the Site of Anti-nociceptive Action of Cyclooxygenase Inhibitors and the Involvement of Cyclooxygenase Products in Central Mechanisms of Nociception.
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| 650 |
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|a Pharmacology.
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| 650 |
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|a Biochemical engineering.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Biochemical Engineering.
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| 700 |
1 |
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|a Ayoub, Samir S.
|e editor.
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| 700 |
1 |
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|a Flower, Roderick J.
|e editor.
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| 700 |
1 |
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|a Seed, Michael.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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