Genome Editing : The Next Step in Gene Therapy /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Cathomen, Toni. (Editor ), Hirsch, Matthew. (Editor ), Porteus, Matthew. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Advances in Experimental Medicine and Biology, 895
Materias:
Tabla de Contenidos:
  • 1. Gene Editing: Double-Strand Break Induced Gene Targeting and Mutagenesis 20 Years Later
  • 2. The Development and Use of Zinc-Finger Nucleases
  • 3.The Use and Development of TAL Effector Nucleases
  • 4. Genome Editing for Neuromuscular Diseases
  • 5. Phage Integrases for Genome Editing
  • 6. Precise Genome Modification Using Triplex Forming Oligonucleotides and Peptide Nucleic Acids
  • 7. Genome Editing by Aptamer-Guided Gene Targeting
  • 8. Stimulation of AAV Gene Editing via DSB Repair
  • 9. Engineered Nucleases and Trinucleotide Repeat Diseases
  • 10. Using Engineered Nucleases to Create HIV-Resistant Cells
  • 11. Strategies to Determine Off-Target Effects of Engineered Nucleases.