Current Trends in Monoclonal Antibody Development and Manufacturing /
| Autor Corporativo: | |
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| Otros Autores: | , , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2010.
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| Edición: | 1st ed. 2010. |
| Colección: | Biotechnology: Pharmaceutical Aspects ;
XI |
| Materias: |
Tabla de Contenidos:
- Design Of Therapeutic MABS
- CDR Repair: A Novel Approach to Antibody Humanization
- Nanobodies, Single-Domain Antigen-Binding Fragments of Camelid Heavy-Chain Antibodies
- Expression and Production of MABS
- GPEx® A Flexible Method for the Rapid Generation of Stable, High Expressing, Antibody Producing Mammalian Cell Lines
- Advancing Our Cell Culture Platform: Incorporating Lessons Learned and New Technologies
- Recovery and Purification
- Addressing Changes Associated with Technology Transfer: A Case Study
- Concepts for Disposables in Biopharmaceutical Manufacture
- Formulation and Delivery
- Formulation and Delivery Issues for Monoclonal Antibody Therapeutics
- Challenges in the Development of High Protein Concentration Formulations
- Protein Immobilization by Crystallization and Precipitation: An Alternative to Lyophilization
- Analytics and Specification Setting for MABS
- Characterizing High Affinity Antigen/Antibody Complexes by Kinetic and Equilibrium Based Methods
- Analytical Characterization of Monoclonal Antibodies: Linking Structure to Function
- Analysis of Irreversible Aggregation, Reversible Self-association and Fragmentation of Monoclonal Antibodies by Analytical Ultracentrifugation
- Biophysical Signatures of Monoclonal Antibodies
- Pharmacokinetics and Immunogenicity
- Impact of Fc Glycosylation on Monoclonal Antibody Effector Functions and Degradation by Proteases
- Immunogenicity Assessment of Antibody Therapeutics
- Armed Antibodies and New Classes of Antibodies
- Production of Monoclonal Antibodies in E. coli
- Recent Advancements in the Use of Antibody Drug Conjugates for Cancer Therapy
- Antibody Radiolabeling.