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| LEADER |
03062nam a22003375i 4500 |
| 001 |
000280630 |
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20200929154108.0 |
| 007 |
cr nn 008mamaa |
| 008 |
181213s2019 xxu| s |||| 0|eng d |
| 020 |
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|a 9781493989553
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| 024 |
7 |
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|a 10.1007/978-1-4939-8955-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Computational Methods for Drug Repurposing /
|c edited by Quentin Vanhaelen.
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| 250 |
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|a 1st ed. 2019.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2019.
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| 300 |
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|a XI, 332 p. 103 illus., 82 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1903
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| 505 |
0 |
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|a Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing -- Performing an In Silico Repurposing of Existing Drugs by Combining Virtual Screening and Molecular Dynamics Simulation -- Repurposing Drugs Based on Evolutionary Relationships between Targets of Approved Drugs and Proteins of Interest -- Drug Repositioning by Mining Adverse Event Data in ClinicalTrials.gov -- Transcriptomic Data Mining and Repurposing for Computational Drug Discovery -- Network-Based Drug-Repositioning: Approaches, Resources, and Research Directions -- A Computational Bipartite-Graph-Based Drug Repurposing Method -- Implementation of a Pipeline Using Disease-Disease Associations for Computational Drug Repurposing -- An Application of Computational Drug Repurposing Based on Transcriptomic Signatures -- Drug-Induced Expression-Based Computational Repurposing of Small Molecules Affecting Transcription Factor Activity -- A Drug Repurposing Method Based on Drug-Drug Interaction Networks and Using Energy Model Layouts -- Integrating Biological Networks for Drug Target Prediction and Prioritization -- Using Drug Expression Profiles and Machine Learning Approach for Drug Repurposing -- Computational Prediction of Drug-Target Interactions via Ensemble Learning -- A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization -- Machine Learning Approach for Predicting New Uses of Existing Drugs and Evaluation of Their Reliabilities -- A Drug-Target Network-Based Supervised Machine Learning Repurposing Method Allowing the Use of Multiple Heterogeneous Information Sources -- Heter-LP: A Heterogeneous Label Propagation Method for Drug Repositioning -- Tripartite Network-Based Repurposing Method Using Deep Learning to Compute Similarities for Drug-Target Prediction.
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| 650 |
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0 |
|a Pharmaceutical technology.
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| 650 |
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0 |
|a Medicinal chemistry.
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| 650 |
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0 |
|a Bioinformatics.
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| 650 |
1 |
4 |
|a Pharmaceutical Sciences/Technology.
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| 650 |
2 |
4 |
|a Medicinal Chemistry.
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| 650 |
2 |
4 |
|a Computational Biology/Bioinformatics.
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| 700 |
1 |
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|a Vanhaelen, Quentin.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|