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190823s2019 xxu| s |||| 0|eng d |
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|a 9781493996667
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| 024 |
7 |
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|a 10.1007/978-1-4939-9666-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a G-Quadruplex Nucleic Acids :
|b Methods and Protocols /
|c edited by Danzhou Yang, Clement Lin.
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| 250 |
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|a 1st ed. 2019.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2019.
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| 300 |
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|a XIV, 437 p. 121 illus., 95 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 2035
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| 505 |
0 |
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|a G-Quadruplex DNA and RNA -- CD Study of the G-Quadruplex Conformation -- Revealing the Energetics of Ligand-Quadruplex Interactions using Isothermal Titration Calorimetry -- Biosensor-Surface Plasmon Resonance: Label Free Method for Investigation of Small Molecule-Quadruplex Nucleic Acid Interactions -- Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation -- Mass Spectroscopic Study of G-Quadruplex -- G-Quadruplex Stability from DSC Measurements -- X-Ray Crystallographic Studies of G-Quadruplex Structures -- NMR Studies of G-Quadruplex Structures and G-Quadruplex-Interactive Compounds -- Using Molecular Dynamics Free Energy Simulation to Compute Binding Affinities of DNA G-Quadruplex Ligands -- Electrophoretic Mobility Shift Assay and Dimethyl Sulfate Footprinting for Characterization of G-Quadruplexes and G-Quadruplex-Protein Complexes -- A DNA Polymerase Stop Assay for Characterization of G-Quadruplex Formation and Identification of G-Quadruplex-Interactive Compounds -- Chromatin Immunoprecipitation Assay to Analyze the Effect of G-Quadruplex Interactive Agents on the Binding of RNA Polymerase II and Transcription Factors to a Target Promoter Region -- Characterization of Co-Transcriptional Formation of G-Quadruplexes in Double-Stranded DNA -- Quantitative Analysis of Stall of Replicating DNA Polymerase by G-Quadruplex Formation -- Single-Molecule Investigations of G-Quadruplex -- Direct Observation of the Formation and Dissociation of Double-Stranded DNA Containing G-Quadruplex/i-motif Sequences in the DNA Origami Frame using High-Speed AFM -- G-Quadruplex and Protein Binding by Single-Molecule FRET Microscopy -- High-Throughput Screening of G-Quadruplex Ligands by FRET Assay -- Targeting G-Quadruplexes with PNA Oligomers -- Primer-Modified G-Quadruplex-Au Nanoparticles for Colorimetric Assay of Human Telomerase Activity and Initial Screening of Telomerase Inhibitors -- Heme•G-Quadruplex DNAzymes: Conditions for Maximizing their Peroxidase Activity -- In Vivo Chemical Probing for G-Quadruplex Formation -- G-Quadruplex Visualization In Cells via Antibody and Fluorescence Probe -- In Cell NMR Spectroscopy: Investigation of G-Quadruplex Structures inside Living Xenopus laevis Oocytes -- 19F NMR Spectroscopy for the Analysis of DNA G-Quadruplex Structures using 19F-labeled Nucleobase.
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| 650 |
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|a Human genetics.
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| 650 |
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|a Mass spectrometry.
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| 650 |
1 |
4 |
|a Human Genetics.
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| 650 |
2 |
4 |
|a Mass Spectrometry.
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| 700 |
1 |
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|a Yang, Danzhou.
|e editor.
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| 700 |
1 |
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|a Lin, Clement.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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