G-Quadruplex Nucleic Acids : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Yang, Danzhou. (Editor ), Lin, Clement. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2019.
Edición:1st ed. 2019.
Colección:Methods in Molecular Biology, 2035
Materias:
Tabla de Contenidos:
  • G-Quadruplex DNA and RNA
  • CD Study of the G-Quadruplex Conformation
  • Revealing the Energetics of Ligand-Quadruplex Interactions using Isothermal Titration Calorimetry
  • Biosensor-Surface Plasmon Resonance: Label Free Method for Investigation of Small Molecule-Quadruplex Nucleic Acid Interactions
  • Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation
  • Mass Spectroscopic Study of G-Quadruplex
  • G-Quadruplex Stability from DSC Measurements
  • X-Ray Crystallographic Studies of G-Quadruplex Structures
  • NMR Studies of G-Quadruplex Structures and G-Quadruplex-Interactive Compounds
  • Using Molecular Dynamics Free Energy Simulation to Compute Binding Affinities of DNA G-Quadruplex Ligands
  • Electrophoretic Mobility Shift Assay and Dimethyl Sulfate Footprinting for Characterization of G-Quadruplexes and G-Quadruplex-Protein Complexes
  • A DNA Polymerase Stop Assay for Characterization of G-Quadruplex Formation and Identification of G-Quadruplex-Interactive Compounds
  • Chromatin Immunoprecipitation Assay to Analyze the Effect of G-Quadruplex Interactive Agents on the Binding of RNA Polymerase II and Transcription Factors to a Target Promoter Region
  • Characterization of Co-Transcriptional Formation of G-Quadruplexes in Double-Stranded DNA
  • Quantitative Analysis of Stall of Replicating DNA Polymerase by G-Quadruplex Formation
  • Single-Molecule Investigations of G-Quadruplex
  • Direct Observation of the Formation and Dissociation of Double-Stranded DNA Containing G-Quadruplex/i-motif Sequences in the DNA Origami Frame using High-Speed AFM
  • G-Quadruplex and Protein Binding by Single-Molecule FRET Microscopy
  • High-Throughput Screening of G-Quadruplex Ligands by FRET Assay
  • Targeting G-Quadruplexes with PNA Oligomers
  • Primer-Modified G-Quadruplex-Au Nanoparticles for Colorimetric Assay of Human Telomerase Activity and Initial Screening of Telomerase Inhibitors
  • Heme•G-Quadruplex DNAzymes: Conditions for Maximizing their Peroxidase Activity
  • In Vivo Chemical Probing for G-Quadruplex Formation
  • G-Quadruplex Visualization In Cells via Antibody and Fluorescence Probe
  • In Cell NMR Spectroscopy: Investigation of G-Quadruplex Structures inside Living Xenopus laevis Oocytes
  • 19F NMR Spectroscopy for the Analysis of DNA G-Quadruplex Structures using 19F-labeled Nucleobase.