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03086nam a22003255i 4500 |
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000280898 |
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20211108155704.0 |
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cr nn 008mamaa |
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100301s2009 xxu| s |||| 0|eng d |
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|a 9781603270885
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| 024 |
7 |
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|a 10.1007/978-1-60327-088-5
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response /
|c edited by Federico Innocenti.
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| 250 |
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|a 1st ed. 2009.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2009.
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| 300 |
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|a XIV, 378 p. 53 illus., 3 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Cancer Drug Discovery and Development,
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| 505 |
0 |
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|a Genomic Experimental Approaches in Oncology -- Toward the Realization of the Promise of Microarrays in Oncology -- Cell-Based Models to Identify Genetic Variants Contributing to Anticancer Drug Response -- Proteomic Analysis in Cancer Patients -- MicroRNAs and Discovery of New Targets -- Pharmacogenomics of the National Cancer Institute’s 60-Tumor Cell Panel -- Use of Single-Nucleotide Polymorphism Array for Tumor Aberrations in Gene Copy Numbers -- Pharmacogenomics of Toxicity and Response of Chemotherapy -- Concordance Between Tumor and Germline DNA -- Epidermal Growth Factor Receptor Mutations and Sensitivity to Selective Kinase Inhibitors in Human Lung Cancer -- BCR-ABL Mutations and Imatinib Resistance in Chronic Myeloid Leukemia Patients -- Role of Thymidylate Synthase Gene Variations in Colorectal Cancer Patients -- Thiopurines in the Treatment of Childhood Acute Lymphoblastic Leukemia and Genetic Variants of the Thiopurine S-Methyltransferase Gene -- Impact of Polymorphisms on the Clinical Outcomes of Monoclonal Antibody Therapy Against Hematologic Malignancies -- DNA Repair and Mitotic Checkpoint Genes as Potential Predictors of Chemotherapy Response in Non-Small-Cell Lung Cancer -- Dihydropyrimidine Dehydrogenase (Dpyd) Gene Polymorphism: Portrait of a Serial Killer -- Impact of UDP-Glucuronosyltransferase 1A Haplotypes on Irinotecan Treatment -- Microarray Profiling in Breast Cancer Patients -- Role of the Folate-Pathway and the Thymidylate Synthase Genes in Pediatric Acute Lymphoblastic Leukemia Treatment Response -- Pharmacogenomics in Clinical Drug Development in Oncology -- Pharmacogenomics in Drug Development: A Pharmaceutical Industry Perspective -- Identification of Pharmacogenomic Biomarker Classifiers in Cancer Drug Development -- Toxicogenomics Application to Oncology Drug Development -- Strategies to Identify Pharmacogenomic Biomarkers: Candidate Gene, Pathway-Based, and Genome-Wide Approaches.
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| 650 |
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|a Cancer research.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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|a Human genetics.
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| 650 |
1 |
4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Innocenti, Federico.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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