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120905s2013 xxu| s |||| 0|eng d |
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|a 9781441999672
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|a 10.1007/978-1-4419-9967-2
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a Epigenetic Alterations in Oncogenesis /
|c edited by Adam R. Karpf.
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|a 1st ed. 2013.
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|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2013.
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|a XVI, 348 p. :
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
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|2 rdacarrier
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|a Preface -- Section I: Epigenetic Marks and Mechanisms -- DNA methyltransferases (DNMTs), DNA damage repair, and cancer -- DNA hypomethylation and hemimethylation in cancer -- Ten Eleven Translocation (TET) Enzymes and 5-hydroxymethylation in Mammalian Development and Cancer -- Altered histone modifications in cancer -- Nucleosome occupancy and gene regulation during tumorigenesis -- Section II: The Impact of Epigenetic Alterations on Cancer Biology -- Epigenetic regulation of miRNAs in cancer -- DNA hypomethylation and activation of germline-specific genes in cancer -- APC and DNA demethylation in cell fate specification and intestinal cancer -- Epigenetic changes during cell transformation -- Epigenetic reprogramming of mesenchymal stem cells -- Section III: Clinical Implications and Analysis Methods -- Environmental toxicants, epigenetics, and cancer -- Blood derived DNA methylation markers of cancer risk -- Epigenetic therapies in MDS and AML -- Epigenetic targeting therapies to overcome chemotherapy resistance -- Methods for cancer epigenome analysis -- Index.
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|a Cancer research.
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|a Human genetics.
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|a Oncology .
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|a Cancer Research.
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|a Human Genetics.
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|a Oncology.
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|a Karpf, Adam R.
|e editor.
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|a SpringerLink (Online service)
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|t Springer eBooks
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