Epigenetic Alterations in Oncogenesis /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2013.
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| Edición: | 1st ed. 2013. |
| Materias: |
Tabla de Contenidos:
- Preface
- Section I: Epigenetic Marks and Mechanisms
- DNA methyltransferases (DNMTs), DNA damage repair, and cancer
- DNA hypomethylation and hemimethylation in cancer
- Ten Eleven Translocation (TET) Enzymes and 5-hydroxymethylation in Mammalian Development and Cancer
- Altered histone modifications in cancer
- Nucleosome occupancy and gene regulation during tumorigenesis
- Section II: The Impact of Epigenetic Alterations on Cancer Biology
- Epigenetic regulation of miRNAs in cancer
- DNA hypomethylation and activation of germline-specific genes in cancer
- APC and DNA demethylation in cell fate specification and intestinal cancer
- Epigenetic changes during cell transformation
- Epigenetic reprogramming of mesenchymal stem cells
- Section III: Clinical Implications and Analysis Methods
- Environmental toxicants, epigenetics, and cancer
- Blood derived DNA methylation markers of cancer risk
- Epigenetic therapies in MDS and AML
- Epigenetic targeting therapies to overcome chemotherapy resistance
- Methods for cancer epigenome analysis
- Index.