G Protein-Coupled Receptors - Modeling and Simulation /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Filizola, Marta. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Advances in Experimental Medicine and Biology, 796
Materias:
Tabla de Contenidos:
  • Preface. Section I Progress in Structural Modeling of GPCRs
  • The GPCR Crystallography Boom: Providing an Invaluable Source of Structural Information and Expanding the Scope of Homology Modeling
  • Modeling of G Protein-Coupled Receptors Using Crystal Structures: From Monomers to Signaling Complexes. Section II. GPCRs in Motion: Insights from Simulations
  • Structure and Dynamics of G Protein-Coupled Receptors
  • How the Dynamic Properties and Functional Mechanisms of GPCRs are Modulated by their Coupling to the Membrane Environment
  • Coarse-Grained Molecular Dynamics Provides Insight into the Interactions of Lipids and Cholesterol with Rhodopsin
  • Beyond Standard Molecular Dynamics: Investigating the Molecular Mechanisms of G Protein-Coupled Receptors with Enhanced Molecular Dynamics Methods. Section III. GPCR-Focused Rational Design and Mathematical Modeling
  • From Three-Dimensional GPCR Structure to Rational Ligand Discovery
  • Mathematical Modeling Of G Protein-Coupled Receptor Function: What Can We Learn From Empirical And Mechanistic Models? Section IV. Bioinformatics Tools and Resources for GPCRs
  • GPCRs & Company: Databases and Servers for GPCRs and Interacting Partners
  • Bioinformatics Tools for Predicting GPCR Gene Functions. Index.