Gene Therapy of Cancer : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Walther, Wolfgang. (Editor ), Stein, Ulrike S. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2009.
Edición:2nd ed. 2009.
Colección:Methods in Molecular Biology, 542
Materias:
Tabla de Contenidos:
  • Experimental Approaches in Cancer Gene Therapy: Introduction
  • The Development of Gene Therapy: From Monogenic Recessive Disorders to Complex Diseases Such as Cancer
  • Vectorology for Cancer Gene Therapy
  • Designing Adenoviral Vectors for Tumor-Specific Targeting
  • Analysis of HSV Oncolytic Virotherapy in Organotypic Cultures
  • Use of Minicircle Plasmids for Gene Therapy
  • Transposable Elements as Plasmid-Based Vectors for Long-Term Gene Transfer into Tumors
  • Designing Plasmid Vectors
  • Development of Bacterial Vectors for Tumor-Targeted Gene Therapy
  • Nonviral Transfer Technologies in Cancer Gene Therapy
  • Electroporative Gene Transfer
  • Gene Gun Delivery Systems for Cancer Vaccine Approaches
  • Ultrasound-Mediated Gene Transfection
  • Nonviral Jet-Injection Technology for Intratumoral In Vivo Gene Transfer of Naked DNA
  • Experimental Studies in Cancer Gene Therapy
  • Methods for Constructing and Evaluating Antitumor DNA Vaccines
  • Immunity of Lentiviral Vector-Modified Dendritic Cells
  • Saporin Suicide Gene Therapy
  • Using In Vivo Biopanning for the Development of Radiation-Guided Drug Delivery Systems
  • Chemosensitization of Tumor Cells: Inactivation of Nuclear Factor-Kappa B Associated with Chemosensitivity in Melanoma Cells After Combination Treatment with E2F-1 and Doxorubicin
  • Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
  • Silencing Epidermal Growth Factor Receptor by RNA Interference in Glioma
  • Delivery of Phosphorodiamidate Morpholino Antisense Oligomers in Cancer Cells
  • Use of RNA Aptamers for the Modulation of Cancer Cell Signaling
  • G-Rich Oligonucleotides for Cancer Treatment
  • Clinical Approaches in Cancer Gene Therapy - Requirements for Clinical Gene Therapy Trials
  • Regulatory Aspects for Translating Gene Therapy Research into the Clinic
  • Ethics of Cancer Gene Transfer Clinical Research
  • Virus Production for Clinical Gene Therapy
  • Production of Plasmid DNA as Pharmaceutical
  • Clinical Protocols in Cancer Gene Therapy
  • Gene Immunotherapy for Non-Small Cell Lung Cancer
  • Gene Therapy for Antitumor Vaccination
  • HSV-tk/IL-2 Gene Therapy for Glioblastoma Multiforme
  • Construction and Characterization of an Oncolytic HSV Vector Containing a Fusogenic Glycoprotein and Prodrug Activation for Enhanced Local Tumor Control
  • Newcastle Disease Virus: A Promising Vector for Viral Therapy, Immune Therapy, and Gene Therapy of Cancer
  • Oncolytic Viral Therapy Using Reovirus
  • Design and Testing of Novel Oncolytic Vaccinia Strains
  • Tumor-Targeted Salmonella typhimurium Overexpressing Cytosine Deaminase: A Novel, Tumor-Selective Therapy
  • Chemoprotection by Transfer of Resistance Genes
  • Phase I Clinical Trial of Locoregional Administration of the Oncolytic Adenovirus ONYX-015 in Combination with Mitomycin-C, Doxorubicin, and Cisplatin Chemotherapy in Patients with Advanced Sarcomas.