DNA Alterations in Lynch Syndrome : Advances in molecular diagnosis and genetic counselling /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Dordrecht :
Springer Netherlands : Imprint: Springer,
2013.
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| Edición: | 1st ed. 2013. |
| Materias: |
Tabla de Contenidos:
- Preface
- Historical Development of Lynch Syndrome
- Molecular Mechanisms and Functions of DNA Mismatch Repair
- New Insights into Lynch Syndrome Diagnosis
- Genetic Testing, an Optimal Strategy for Lynch Syndrome Identification
- Functional Analyses Help to Assess the Pathogenicity of MMR Gene Variants of Uncertain Significance
- The Role of Epimutations of the Mismatch Repair Genes in the Development of Lynch Syndrome Related Cancers
- Mutations in non-MMR Genes Modifying or Mimicking Lynch Syndrome Phenotype
- Lynch Syndrome: Genetic Counselling of at-risk Individuals and Families
- Index.