Genotoxicity and Carcinogenicity Testing of Pharmaceuticals /
| Autor Corporativo: | |
|---|---|
| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
|
| Edición: | 1st ed. 2015. |
| Materias: |
Tabla de Contenidos:
- Introduction
- History and Current Regulatory Requirements
- Genotoxicity Testing of API and Impurities
- New Emerging Genotoxicity Tests
- Carcinogenicity Testing of Small Molecules
- Alternatives to the 2-Year Rodent Studies
- Addressing Positive Findings in Carcinogenicity Studies
- Investigating Tumor Signals in Clinical Trials
- Tumor Promoters
- Carcinogenicity Testing of Biologics
- In Silico Predictive Tests.