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121116s2013 ne | s |||| 0|eng d |
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|a 9789400745254
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|a 10.1007/978-94-007-4525-4
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a Epigenetics: Development and Disease /
|c edited by Tapas Kumar Kundu.
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| 250 |
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|a 1st ed. 2013.
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| 260 |
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a XXVI, 689 p. 70 illus., 56 illus. in color. :
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Subcellular Biochemistry,
|v 61
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|a PART I: EPIGENETICS AND EVOLUTION -- 1.1 Chromatin Organization, Epigenetics and Differentiation: An evolutionary perspective -- 1.2 Secondary structures of the core histone N-terminal tails: their role in regulating chromatin structure -- 1.3 Megabase replication domains along the human genome: Relation to chromatin structure and genome organization -- 1.4 Role of DNA methyltransferases in epigenetic regulation in bacteria -- PART II: DEVELOPMENTAL EPIGENETICS -- 2.1 Metabolic aspects of epigenome: Coupling of S-adenosylmethionine synthesis and gene regulation on chromatin by SAMIT module -- 2.2 Epigenetic regulation of male germ cell differentiation -- 2.3 Epigenetic Regulation of Skeletal Muscle Development and Differentiation -- 2.4 Small changes, big effects: chromatin goes aging -- 2.5 Homeotic gene regulation: A paradigm for epigenetic mechanisms underlying organismal development -- PART III: EPIGENETICS AND TRANSCRIPTION REGULATION -- 3.1 Basic mechanisms in RNA Polymerase I transcription of the ribosomal RNA genes -- 3.2 The RNA polymerase II transcriptional machinery and its epigenetic context -- 3.3 RNA polymerase III transcriptions - regulated by chromatin structure and regulator of nuclear chromatin organization -- 3.4. The Role of DNA Methylation and Histone Modifications in Transcriptional Regulation in humans -- 3.5 Histone variants and Transcription regulation -- 3.6 Noncoding RNAs in Chromatin Organization and Transcription Regulation: An Epigenetic View -- 3.7 Chromatin structure and organization: the relation with gene expression during development and disease -- PART IV: EPIGENETICS AND DISEASE -- 4.1 Epigenetics and cancer: Development, Differentiation and Pathobiology -- 4.2 Epigenetic Regulation of Cancer Stem Cell Gene Expression -- 4.3 Role of Epigenetic Mechanisms in the Vascular Complications of Diabetes -- 4.4 Epigenetic changes in inflammatory and autoimmune diseases -- 4.5 Epigenetic regulation of HIV-1 persistence and evolving strategies for virus eradication -- 4.6 Epigenetics in Parkinson’s and Alzheimer’s diseases -- 4.7 Cellular Redox, Epigenetics and Diseases -- PART V: UNDERSTANDING OF EPIGENETICS: A CHEMICAL BIOLOGY APPROACH AND EPIGENETIC THERAPY -- 5.1 Stem cell plasticity in development and cancer: Epigenetic origin of cancer stem cells -- 5.2 Histone acetylation as a therapeutic target- Implication of nanodelivery -- 5.3 DNA methylation and Cancer -- 5.4 Role of epigenetics in inflammation-associated diseases -- 5.5 Plasmodium falciparum: Epigenetic control of var gene regulation and disease.
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|a Gene expression.
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| 650 |
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|a Posttranslational modification.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Developmental biology.
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| 650 |
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|a Stem cells.
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|a Gene Expression.
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| 650 |
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|a Posttranslational Modification.
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| 650 |
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|a Cancer Research.
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| 650 |
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|a Developmental Biology.
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| 650 |
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|a Stem Cells.
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| 700 |
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|a Kundu, Tapas Kumar.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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