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120925s2013 xxu| s |||| 0|eng d |
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|a 9781627030502
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| 024 |
7 |
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|a 10.1007/978-1-62703-050-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Computational Toxicology :
|b Volume I /
|c edited by Brad Reisfeld, Arthur N. Mayeno.
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| 250 |
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|a 1st ed. 2013.
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| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
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| 300 |
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|a XI, 613 p. 157 illus., 75 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 929
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| 505 |
0 |
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|a What is Computational Toxicology? -- Computational Toxicology – Application in Environmental Chemicals -- Role of Computational Methods in Pharmaceutical Sciences -- Best Practices in Mathematical Modeling -- Tools and Techniques -- Prediction of Physicochemical Properties -- Informing Mechanistic Toxicology with Computational Molecular Models -- Chemical Structure Representations and Applications in Computational Toxicity -- Accessing and Using Chemical Property Databases -- Accessing, Using and Creating Chemical Property Databases for Computational Toxicology Modeling -- Molecular Dynamics -- Introduction to Pharmacokinetics in Clinical Toxicology.-Modeling of Absorption -- Prediction of Pharmacokinetic Parameters -- Ligand – And Structure-Based Pregnane X Receptor Models -- Non-Compartmental Analysis -- Compartmental Modeling in the Analysis of Biological Systems -- Physicologically Based Pharmacokinetic/Toxicokinetic Modeling -- Interspecies Extrapolation -- Population Effects and Variability -- Mechanism-Based Pharmacodynamic Modeling.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Bioinformatics .
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| 650 |
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0 |
|a Computational biology .
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Computer Appl. in Life Sciences.
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| 700 |
1 |
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|a Reisfeld, Brad.
|e editor.
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| 700 |
1 |
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|a Mayeno, Arthur N.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|