Computational Toxicology : Volume I /
| Autor Corporativo: | |
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| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2013.
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| Edición: | 1st ed. 2013. |
| Colección: | Methods in Molecular Biology,
929 |
| Materias: |
Tabla de Contenidos:
- What is Computational Toxicology?
- Computational Toxicology – Application in Environmental Chemicals
- Role of Computational Methods in Pharmaceutical Sciences
- Best Practices in Mathematical Modeling
- Tools and Techniques
- Prediction of Physicochemical Properties
- Informing Mechanistic Toxicology with Computational Molecular Models
- Chemical Structure Representations and Applications in Computational Toxicity
- Accessing and Using Chemical Property Databases
- Accessing, Using and Creating Chemical Property Databases for Computational Toxicology Modeling
- Molecular Dynamics
- Introduction to Pharmacokinetics in Clinical Toxicology.-Modeling of Absorption
- Prediction of Pharmacokinetic Parameters
- Ligand – And Structure-Based Pregnane X Receptor Models
- Non-Compartmental Analysis
- Compartmental Modeling in the Analysis of Biological Systems
- Physicologically Based Pharmacokinetic/Toxicokinetic Modeling
- Interspecies Extrapolation
- Population Effects and Variability
- Mechanism-Based Pharmacodynamic Modeling.