Erythropoietins, Erythropoietic Factors, and Erythropoiesis : Molecular, Cellular, Preclinical, and Clinical Biology /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Elliott, Steven G. (Editor), Foote, MaryAnn. (Editor), Molineux, Graham. (Editor)
Format: eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2009.
Edition:2nd ed. 2009.
Series:Milestones in Drug Therapy,
Subjects:
Table of Contents:
  • Background
  • Erythropoiesis: an overview
  • Regulation of endogenous erythropoietin production
  • Biology of erythropoietin
  • Erythropoiesis-genetic abnormalities
  • Erythropoiesis-stimulating agents
  • Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin
  • Commercial production of recombinant erythropoietins
  • Biosimilar epoetins
  • New molecules and formulations
  • Erythropoietin receptor
  • Structural basis for the signal transduction of erythropoietin
  • Intracellular signaling by the erythropoietin receptor
  • Mechanism of erythropoietin receptor activation
  • Clinical utility
  • Pharmacokinetics of erythropoiesis-stimulating agents
  • Use of erythropoietic stimulating agents in the setting of renal disease
  • Abuse of recombinant erythropoietins and blood products by athletes
  • Role and regulation of iron metabolism in erythropoiesis and disease
  • Nonhematopoietic effects of erythropoiesis-stimulating agents.