Death Receptors and Cognate Ligands in Cancer /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Kalthoff, Holger. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2009.
Edición:1st ed. 2009.
Colección:Results and Problems in Cell Differentiation, 49
Materias:
Tabla de Contenidos:
  • The Role of TNF in Cancer
  • Many Checkpoints on the Road to Cell Death:Regulation of Fas–FasL Interactions and Fas Signaling in Peripheral Immune Responses
  • FasL Expression and Reverse Signalling
  • Impact of TNF-R1 and CD95 Internalization on Apoptotic and Antiapoptotic Signaling
  • Ubiquitination and TNFR1 Signaling
  • From Biochemical Principles of Apoptosis Induction by TRAIL to Application in Tumour Therapy
  • Therapeutic Targeting of TWEAK/Fn14 in Cancer: Exploiting the Intrinsic Tumor Cell Killing Capacity of the Pathway
  • APRIL in B-cell Malignancies and Autoimmunity
  • Autophagy in Cancer and Chemotherapy
  • Glucocorticoid-Mediated Apoptosis Resistance of Solid Tumors
  • Targeting Death-Receptors in Radiation Therapy
  • Death Ligands Designed to Kill: Development and Application of Targeted Cancer Therapeutics Based on Proapoptotic TNF Family Ligands.