Drug Safety Evaluation : Methods and Protocols /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2017.
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| Edición: | 2nd ed. 2017. |
| Colección: | Methods in Molecular Biology,
1641 |
| Materias: |
Tabla de Contenidos:
- Nonclinical Development of Combination Drugs
- Juvenile Non-Clinical Safety Studies in Support of Pediatric Drug Development
- Procedures of Necropsy and Tissue Sampling
- Tissue Sampling and Processing for Histopathology Evaluation
- Principles and Methods of Immunohistochemistry
- Applications of Mass Spectrometry Imaging for Safety Evaluation
- In vivo rat T-lymphocyte Pig-a assay: detection and expansion of cells deficient in the GPI-anchored CD48 surface marker for analysis of mutation in the endogenous Pig-a gene
- Detection of In Vivo Mutation in the Pig-a Gene of Mouse Bone Marrow Erythroids
- The Use of Bacterial Repair Endonucleases in the Comet Assay
- Automated Patch-Clamp methods for the hERG Cardiac Potassium Channel
- Impedance Measurement in Induced Pluripotent Stem Cell Derived Cardiomyocytes
- Target Safety Assessment: Strategies and Resources
- NMR and MS Methods for Metabolomics
- Protocols and Applications of Cellular Metabolomics in Safety Studies Using Precision-Cut Tissue Slices and Carbon 13 NMR
- Statistical Analysis of Quantitative RT-PCR Results
- Evaluation of Mitochondrial Respiration in Cultured Rat Hepatocytes
- FETAX Assay for Evaluation of Developmental Toxicity
- Evaluation of Embryotoxicity Using the Zebrafish Model
- Absolute Quantification of Toxicological Biomarkers via Mass Spectrometry
- Next-Generation Sequencing to investigate urinary microRNAs from Macaca fascicularis (Cynomolgus Monkey)
- Quantitative RT-PCR for MicroRNAs in Biofluids
- Chromogenic In Situ Hybridization Methods for microRNA Biomarker Monitoring of Drug Safety and Efficacy
- Urine Exosome Isolation and Characterization.