|
|
|
|
| LEADER |
02763nam a22003135i 4500 |
| 001 |
000283466 |
| 005 |
20210729150515.0 |
| 007 |
cr nn 008mamaa |
| 008 |
150106s2015 xxu| s |||| 0|eng d |
| 020 |
|
|
|a 9781493923366
|
| 024 |
7 |
|
|a 10.1007/978-1-4939-2336-6
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a G Protein-Coupled Receptor Screening Assays :
|b Methods and Protocols /
|c edited by Duarte Miguel F. Prazeres, Sofia Aires M. Martins.
|
| 250 |
|
|
|a 1st ed. 2015.
|
| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2015.
|
| 300 |
|
|
|a XII, 296 p. 78 illus., 51 illus. in color. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Methods in Molecular Biology,
|v 1272
|
| 505 |
0 |
|
|a G-Protein Coupled Receptors: An Overview of Signaling Mechanisms and Screening Assays -- Time–Resolved FRET Strategy to Screen GPCR Ligands Library -- Homogeneous Fluorescence Anisotropy-Based Assay for Characterization of Ligand Binding Dynamics to GPCRs in Budded Baculoviruses: The Case of Cy3B-NDP-a-MSH Binding to MC4 Receptors -- Construction of Recombinant HEK293 Cell Lines for the Expression of the Neurotensin Receptor NTSR1 -- cAMP Assay for GPCR Ligand Characterization: Application of BacMam Expression System -- Ca2+ Mobilization Assays in GPCR Drug Discovery -- Using Constitutive Activity to Define Appropriate High Throughput Screening Assays for Orphan G Protein-Coupled Receptors -- Monitoring G-Protein Coupled Receptor Activation Using the Protein Fragment Complementation Technique Split TEV -- Quantifying GPCR Internalization: A Focus on the Kisspeptin Receptor -- GPCR Oligomerization Analysis by Means of BRET and dFRAP -- Use of ImageJ to Recover Information from Individual Cells in a G-Protein Coupled Receptor Assay -- Methods to Immobilize GPCR on the Surface of SPR Sensors -- Olfactory Receptor Screening Assay Using Nanovesicle-Immobilized Carbon Nanotube Transistor -- Label-Free Biosensor Assays in GPCR Screening -- Multi-Dimensional GPCR Profiling and Screening Using Impedance-Based Label-Free and Real-Time Assay -- Label-Free Functional Selectivity Assays -- Measurement of Surface-Mediated Ca++ Transients on the Single-Cell Level in a Microfluidic Lab-on-a-chip Environment -- Cell-Based Assays and Animal Models for GPCR Drug Screening -- Computer-Aided Design of GPCR Ligands.
|
| 650 |
|
0 |
|a Pharmacology.
|
| 650 |
|
0 |
|a Proteomics.
|
| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
|
| 650 |
2 |
4 |
|a Proteomics.
|
| 700 |
1 |
|
|a Prazeres, Duarte Miguel F.
|e editor.
|
| 700 |
1 |
|
|a Martins, Sofia Aires M.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|