|
|
|
|
| LEADER |
03001nam a22003855i 4500 |
| 001 |
000283474 |
| 005 |
20211101082432.0 |
| 007 |
cr nn 008mamaa |
| 008 |
100301s2007 gw | s |||| 0|eng d |
| 020 |
|
|
|a 9783540351092
|
| 024 |
7 |
|
|a 10.1007/978-3-540-35109-2
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a Conditional Mutagenesis: An Approach to Disease Models /
|c edited by Robert Feil, Daniel Metzger.
|
| 246 |
3 |
|
|a With contributions by numerous experts
|
| 250 |
|
|
|a 1st ed. 2007.
|
| 260 |
# |
# |
|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 2007.
|
| 300 |
|
|
|a XII, 532 p. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Handbook of Experimental Pharmacology,
|v 178
|
| 505 |
0 |
|
|a Tools for Conditional Mutagenesis -- Conditional Somatic Mutagenesis in the Mouse Using Site-Specific Recombinases -- Cre/loxP-Mediated Chromosome Engineering of the Mouse Genome -- Tetracycline-Controlled Genetic Switches -- Novel Gene Switches -- Improved Embryonic Stem Cell Technologies -- Gene Trap Mutagenesis -- RNA Interference in Mice -- Viral Vectors: A Wide Range of Choices and High Levels of Service -- Conditional Mutagenesis by Cell-Permeable Proteins: Potential, Limitations and Prospects -- Examples of Conditional Disease Models -- Analysis of Mouse Development with Conditional Mutagenesis -- Conditional Mouse Models of Cancer -- Conditional Mutagenesis Reveals Immunological Functions of Widely Expressed Genes: Activation Thresholds, Homeostatic Mechanisms and Disease Models -- Conditional Transgenesis and Recombination to Study the Molecular Mechanisms of Brain Plasticity and Memory -- A Novel Conditional Knockout Strategy Applied to Serotonin Receptors -- Conditional Mouse Models for Friedreich Ataxia, a Neurodegenerative Disorder Associating Cardiomyopathy -- Animal Models in Cardiovascular Diseases: New Insights from Conditional Models -- Conditional Animal Models for the Study of Lipid Metabolism and Lipid Disorders -- Conditional Mouse Models to Study Developmental and Pathophysiological Gene Function in Muscle -- Analysis of Calcium Channels by Conditional Mutagenesis -- Conditional Mutagenesis of G-Protein Coupled Receptors and G-Proteins -- Contribution of Targeted Conditional Somatic Mutagenesis to Deciphering Retinoid X Receptor Functions and to Generating Mouse Models of Human Diseases.
|
| 650 |
|
0 |
|a Pharmacology.
|
| 650 |
|
0 |
|a Molecular biology.
|
| 650 |
|
0 |
|a Human genetics.
|
| 650 |
|
0 |
|a Medical biochemistry.
|
| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
|
| 650 |
2 |
4 |
|a Molecular Medicine.
|
| 650 |
2 |
4 |
|a Human Genetics.
|
| 650 |
2 |
4 |
|a Medical Biochemistry.
|
| 700 |
1 |
|
|a Feil, Robert.
|e editor.
|
| 700 |
1 |
|
|a Metzger, Daniel.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|
| 900 |
|
|
|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|