Conditional Mutagenesis: An Approach to Disease Models /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Feil, Robert. (Editor ), Metzger, Daniel. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
Edición:1st ed. 2007.
Colección:Handbook of Experimental Pharmacology, 178
Materias:
Tabla de Contenidos:
  • Tools for Conditional Mutagenesis
  • Conditional Somatic Mutagenesis in the Mouse Using Site-Specific Recombinases
  • Cre/loxP-Mediated Chromosome Engineering of the Mouse Genome
  • Tetracycline-Controlled Genetic Switches
  • Novel Gene Switches
  • Improved Embryonic Stem Cell Technologies
  • Gene Trap Mutagenesis
  • RNA Interference in Mice
  • Viral Vectors: A Wide Range of Choices and High Levels of Service
  • Conditional Mutagenesis by Cell-Permeable Proteins: Potential, Limitations and Prospects
  • Examples of Conditional Disease Models
  • Analysis of Mouse Development with Conditional Mutagenesis
  • Conditional Mouse Models of Cancer
  • Conditional Mutagenesis Reveals Immunological Functions of Widely Expressed Genes: Activation Thresholds, Homeostatic Mechanisms and Disease Models
  • Conditional Transgenesis and Recombination to Study the Molecular Mechanisms of Brain Plasticity and Memory
  • A Novel Conditional Knockout Strategy Applied to Serotonin Receptors
  • Conditional Mouse Models for Friedreich Ataxia, a Neurodegenerative Disorder Associating Cardiomyopathy
  • Animal Models in Cardiovascular Diseases: New Insights from Conditional Models
  • Conditional Animal Models for the Study of Lipid Metabolism and Lipid Disorders
  • Conditional Mouse Models to Study Developmental and Pathophysiological Gene Function in Muscle
  • Analysis of Calcium Channels by Conditional Mutagenesis
  • Conditional Mutagenesis of G-Protein Coupled Receptors and G-Proteins
  • Contribution of Targeted Conditional Somatic Mutagenesis to Deciphering Retinoid X Receptor Functions and to Generating Mouse Models of Human Diseases.