Methionine Dependence of Cancer and Aging : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hoffman, Robert M. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2019.
Edición:1st ed. 2019.
Colección:Methods in Molecular Biology, 1866
Materias:
Tabla de Contenidos:
  • Methods to Study the Role of Methionine Restricted Diet and Methioninase in Cancer Growth Control
  • Altered Methionine Metabolism in Cancer Cells
  • Linkage of Methionine-Dependence and Other Features of Malignancy
  • Isolation and Characterization of Methionine Independent Clones from Methionine Dependent Cancer Cells
  • Tumor-Specific S/G2-Phase Cell Cycle Arrest of Cancer Cells by Methionine Restriction
  • Preclinical Breast Cancer Models to Investigate Metabolic Priming by Methionine Restriction
  • Efficacy of Methionine-Restricted Diets on Cancers In Vivo
  • Dietary Methionine-Restriction Based Cancer Chemotherapy in Rodents
  • Clinical Studies of Methionine-Restricted Diets for Cancer Patients
  • Development of Recombinant Methioninase for Cancer Treatment
  • Methioninase Cell-Cycle Trap Cancer Chemotherapy
  • High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer
  • Total Methionine Restriction Treatment of Cancer
  • Methioninase Gene Therapy
  • Selenomethionine and Methioninase: Selenium Free Radical Anti-Cancer Activity
  • Super and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates
  • Pilot Phase 1 Clinical Trial of Methioninase on High-Stage Cancer Patients: Rapid Depletion of Circulating Methionine
  • Methionine Gamma Lyase from Clostridium sporogenes Increases the Anti-Cancer Effect of Doxorubicin in A549 Cancer Cells In Vitro and Human Cancer Xenografts
  • Methionine Restriction and Life-Span Extension
  • L-[methyl-11C] Methionine-Positron Emission Tomography (MET PET)
  • Is the Hoffman Effect for Methionine Overuse Analogous to the Warburg Effect for Glucose Overuse in Cancer?
  • Recombinant Methioninase as a DNA Demethylation Agent
  • Homocysteine, Thioretinaco Ozonide and Oxidative Phosphorylation in Cancer and Aging: A Proposed Clinical Trial Protocol
  • Afterword - Oral Methioninase: Answer to Cancer and Foundation of Youth?.