Multifaceted Roles of Crystallography in Modern Drug Discovery /
| Autor Corporativo: | |
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| Otros Autores: | , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Dordrecht :
Springer Netherlands : Imprint: Springer,
2015.
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| Edición: | 1st ed. 2015. |
| Colección: | NATO Science for Peace and Security Series A: Chemistry and Biology,
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| Materias: |
Tabla de Contenidos:
- Preface
- List of Contributors
- Engineering G Protein-Coupled Receptors for Drug Design
- Structural Insights into Activation and Allosteric Modulation of G Protein-Coupled Receptors
- Epigenetic Drug Discovery
- Crystallography and Biopharmaceuticals
- Structural Chemistry and Molecular Modeling in the Design of DPP4 Inhibitors
- Considerations for Structure-Based Drug Design Targeting HIV-1 Reverse Transcriptase.-Protein-Ligand Interactions as the Basis for Drug Action
- The Protein Data Bank: Overview and Tools for Drug Discovery
- Small Molecule Crystal Structures in Drug Discovery
- Protein Aggregation and its Prediction
- Importance of Protonation States for the Binding of Ligands to Pharmaceutical Targets
- Protein-Protein Interactions: Structures and Druggability
- Achieving High Quality Ligand Chemistry in Protein-Ligand Crystal Structures for Drug Design
- Molecular Obesity, Potency and Other Addictions in Drug Discovery
- Adventures in Small Molecule Fragment Screening by X-ray Crystallography for Drug Discovery
- Structure-Based Drug Design to Perturb Function of a tRNA-Modifying Enzyme by Active Site and Protein-Protein Interface Inhibition
- Molecular Interaction Analysis for Discovery of Drugs Targeting Enzymes and for Resolving Biological Function.