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150302s2015 ne | s |||| 0|eng d |
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|a 9789401797320
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| 024 |
7 |
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|a 10.1007/978-94-017-9732-0
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Kinesins and Cancer /
|c edited by Frank Kozielski, FSB.
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| 250 |
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|a 1st ed. 2015.
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| 260 |
# |
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2015.
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| 300 |
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|a X, 271 p. 50 illus., 32 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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|a Preface -- The kinesin superfamily -- The discovery and development of Eg5 inhibitors for the clinic -- Mechanism of action of Eg5 inhibitors -- Clinical trials of mitotic kinesin inhibitors -- Kif15; a useful target for anti-cancer therapy?.- Down-regulating CENP-E activity: for better or for worse -- The human kinesin-14 motor KifC1/HSET is an attractive anti-cancer drug target.-Kinesin-13 Microtubule Depolymerizing Proteins as targets for cancer therapy -- Chromokinesins in genome maintenance and cancer -- Kif14: a clinically relevant kinesin and potential target for cancer therapy -- Kinesin-8 members and their potential as biomarker or therapeutic target -- The kinesin-6 members MKLP1, MKLP2 and MPP -- Non-motor spindle proteins as cancer chemotherapy targets -- Inhibitors of mitotic kinesins for cancer treatment: consequences for neurons -- Index.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Cell biology.
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| 650 |
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|a Medicinal chemistry.
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| 650 |
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|a Proteins .
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| 650 |
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|a Oncology .
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| 650 |
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4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Medicinal Chemistry.
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| 650 |
2 |
4 |
|a Protein-Ligand Interactions.
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| 650 |
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4 |
|a Oncology.
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| 700 |
1 |
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|a Kozielski, FSB, Frank.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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