Kinesins and Cancer /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Kozielski, FSB, Frank. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Materias:
Tabla de Contenidos:
  • Preface
  • The kinesin superfamily
  • The discovery and development of Eg5 inhibitors for the clinic
  • Mechanism of action of Eg5 inhibitors
  • Clinical trials of mitotic kinesin inhibitors
  • Kif15; a useful target for anti-cancer therapy?.- Down-regulating CENP-E activity: for better or for worse
  • The human kinesin-14 motor KifC1/HSET is an attractive anti-cancer drug target.-Kinesin-13 Microtubule Depolymerizing Proteins as targets for cancer therapy
  • Chromokinesins in genome maintenance and cancer
  • Kif14: a clinically relevant kinesin and potential target for cancer therapy
  • Kinesin-8 members and their potential as biomarker or therapeutic target
  • The kinesin-6 members MKLP1, MKLP2 and MPP
  • Non-motor spindle proteins as cancer chemotherapy targets
  • Inhibitors of mitotic kinesins for cancer treatment: consequences for neurons
  • Index.