Mouse Models for Drug Discovery : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Proetzel, Gabriele. (Editor ), Wiles, Michael V. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2016.
Edición:2nd ed. 2016.
Colección:Methods in Molecular Biology, 1438
Materias:
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040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 0 |a Mouse Models for Drug Discovery :  |b Methods and Protocols /  |c edited by Gabriele Proetzel, Michael V. Wiles. 
250 |a 2nd ed. 2016. 
260 # # |a New York, NY :  |b Springer New York :  |b Imprint: Humana,  |c 2016. 
300 |a XI, 436 p. 63 illus., 37 illus. in color. :  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in Molecular Biology,  |v 1438 
505 0 |a Genetically Defined Strains in Drug Development and Toxicity Testing -- Simple, Efficient CRISPR-Cas9 Mediated Gene Editing in Mice: Strategies and Methods -- Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice -- Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells -- Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens -- Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies -- A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics -- Germ-Free Mice Model for Studying Host-Microbial Interactions -- Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans -- Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery -- Cholesterol Absorption and Metabolism -- Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening -- Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research -- Murine Model for Colitis-Associated Cancer of the Colon -- Mouse Models for Studying Depression-Like States and Antidepressant Drugs -- Experimental Models of Anxiety for Drug Discovery and Brain Research -- Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders -- Better Utilization of Mouse Models of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the Clinic -- Neuromuscular Disease Models and Analysis -- Brightfield Imaging and Optical Coherence Tomography of the Mouse Posterior Eye -- Mouse Models as Tools to Identify Genetic Pathways for Retinal Degeneration, as Exemplified by Leber's Congenital Amaurosis. 
650 0 |a Pharmacology. 
650 1 4 |a Pharmacology/Toxicology. 
700 1 |a Proetzel, Gabriele.  |e editor. 
700 1 |a Wiles, Michael V.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks