Mouse Models for Drug Discovery : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Proetzel, Gabriele. (Editor ), Wiles, Michael V. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2016.
Edición:2nd ed. 2016.
Colección:Methods in Molecular Biology, 1438
Materias:
Tabla de Contenidos:
  • Genetically Defined Strains in Drug Development and Toxicity Testing
  • Simple, Efficient CRISPR-Cas9 Mediated Gene Editing in Mice: Strategies and Methods
  • Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice
  • Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells
  • Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens
  • Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies
  • A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics
  • Germ-Free Mice Model for Studying Host-Microbial Interactions
  • Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans
  • Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery
  • Cholesterol Absorption and Metabolism
  • Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening
  • Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research
  • Murine Model for Colitis-Associated Cancer of the Colon
  • Mouse Models for Studying Depression-Like States and Antidepressant Drugs
  • Experimental Models of Anxiety for Drug Discovery and Brain Research
  • Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders
  • Better Utilization of Mouse Models of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the Clinic
  • Neuromuscular Disease Models and Analysis
  • Brightfield Imaging and Optical Coherence Tomography of the Mouse Posterior Eye
  • Mouse Models as Tools to Identify Genetic Pathways for Retinal Degeneration, as Exemplified by Leber's Congenital Amaurosis.