High Content Screening : A Powerful Approach to Systems Cell Biology and Phenotypic Drug Discovery /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Johnston, Paul A. (Editor ), Trask, Oscar J. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2018.
Edición:2nd ed. 2018.
Colección:Methods in Molecular Biology, 1683
Materias:
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024 7 |a 10.1007/978-1-4939-7357-6  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 0 |a High Content Screening :  |b A Powerful Approach to Systems Cell Biology and Phenotypic Drug Discovery /  |c edited by Paul A. Johnston, Oscar J. Trask. 
250 |a 2nd ed. 2018. 
260 # # |a New York, NY :  |b Springer New York :  |b Imprint: Humana,  |c 2018. 
300 |a XIII, 397 p. 82 illus., 71 illus. in color. :  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
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338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in Molecular Biology,  |v 1683 
505 0 |a Applications and Caveats on the Utilization of DNA-specific Probes in Cell-based Assays -- General Staining and Segmentation Procedures for High Content Imaging and Analysis -- Tools to Measure Cell Health and Cytotoxicity Using High Content Imaging and Analysis -- Cell-based High Content Analysis of Cell Proliferation and Apoptosis -- Tools to Measure Autophagy using High Content Imaging and Analysis -- Guidelines for Microplate Selection in High Content Imaging -- Quality Control for High-Throughput Imaging Experiments using Machine Learning in CellProfiler -- High Content Screening Approaches That Minimize Confounding Factors in RNAi, CRISPR and Small Molecule Screening -- Strategies and solutions to Maintain and Retain Data from High Content Imaging, Analysis, and Screening Assays -- Live-Cell High Content Screening in Drug Development -- Challenges and Opportunities in Enabling High-Throughput, Miniaturized High-Content Screening -- Translocation Biosensors - Versatile Tools to Probe Protein Functions In Living Cells -- High Content Positional Biosensor Assay to Screen for Compounds that Prevent or Disrupt Androgen Receptor and Transcription Intermediary Factor 2 Protein-Protein Interactions -- High Content Imaging Assays for IL-6-induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines -- Single Cell and Population Level Analysis of HCA Data -- Utilization of Multidimensional Data in the Analysis of Ultra High Throughput High Content Phenotypic Screens -- High Content Screening of Mammalian Primary Cortical Neurons -- Human Derived Neurons and Neural Progenitor Cells in High Content Imaging Applications -- Determination of Hepatotoxicity in iPSC-Derived Hepatocytes by Multiplexed High-Content Assays -- The Generation of Three-Dimensional Head and Neck Cancer Models for Drug Discovery in 384-well Ultra-Low Attachment Microplates -- An Endothelial Cell/Mesenchymal Stem Cell Co-Culture Cord Formation Assay to Model Vascular Biology In Vitro -- High-throughput Automated Chemical Screens in Zebrafish. 
650 0 |a Biotechnology. 
650 1 4 |a Biotechnology. 
700 1 |a Johnston, Paul A.  |e editor. 
700 1 |a Trask, Oscar J.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
900 |a Libro descargado a ALEPH en bloque (proveniente de proveedor)