High Content Screening : A Powerful Approach to Systems Cell Biology and Phenotypic Drug Discovery /
| Autor Corporativo: | |
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| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2018.
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| Edición: | 2nd ed. 2018. |
| Colección: | Methods in Molecular Biology,
1683 |
| Materias: |
Tabla de Contenidos:
- Applications and Caveats on the Utilization of DNA-specific Probes in Cell-based Assays
- General Staining and Segmentation Procedures for High Content Imaging and Analysis
- Tools to Measure Cell Health and Cytotoxicity Using High Content Imaging and Analysis
- Cell-based High Content Analysis of Cell Proliferation and Apoptosis
- Tools to Measure Autophagy using High Content Imaging and Analysis
- Guidelines for Microplate Selection in High Content Imaging
- Quality Control for High-Throughput Imaging Experiments using Machine Learning in CellProfiler
- High Content Screening Approaches That Minimize Confounding Factors in RNAi, CRISPR and Small Molecule Screening
- Strategies and solutions to Maintain and Retain Data from High Content Imaging, Analysis, and Screening Assays
- Live-Cell High Content Screening in Drug Development
- Challenges and Opportunities in Enabling High-Throughput, Miniaturized High-Content Screening
- Translocation Biosensors - Versatile Tools to Probe Protein Functions In Living Cells
- High Content Positional Biosensor Assay to Screen for Compounds that Prevent or Disrupt Androgen Receptor and Transcription Intermediary Factor 2 Protein-Protein Interactions
- High Content Imaging Assays for IL-6-induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines
- Single Cell and Population Level Analysis of HCA Data
- Utilization of Multidimensional Data in the Analysis of Ultra High Throughput High Content Phenotypic Screens
- High Content Screening of Mammalian Primary Cortical Neurons
- Human Derived Neurons and Neural Progenitor Cells in High Content Imaging Applications
- Determination of Hepatotoxicity in iPSC-Derived Hepatocytes by Multiplexed High-Content Assays
- The Generation of Three-Dimensional Head and Neck Cancer Models for Drug Discovery in 384-well Ultra-Low Attachment Microplates
- An Endothelial Cell/Mesenchymal Stem Cell Co-Culture Cord Formation Assay to Model Vascular Biology In Vitro
- High-throughput Automated Chemical Screens in Zebrafish.